Fig. 1
From: Recombinant growth hormone therapy in a girl with costello syndrome: a 4-year observation
![Fig. 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13052-015-0209-4/MediaObjects/13052_2015_209_Fig1_HTML.gif)
The presented 6-year-old girl with Costello syndrome after 30 months of treatment with rhGH. The pictures show typical phenotypic features of the syndrome: loose skin with deep palmar creases (a); abnormal feet position as a result of excessive joint laxity (b)