Fig. 4

Expression of phosphorylated Ras/Raf/Mekl/2/Erkl/2 protein in cerebral cortex of three groups of mice. Note: (a) shows Western blot assay of cerebral cortex phosphorylated Ras/Raf/Mekl/2/Erkl/2 protein expressions in three groups of mice; (b-h) show cerebral cortex Ras, P-A-Raf, P-B-Raf, P-C-Raf, C-Raf, P-Mekl/2 and P-Erkl/2 expressions. In (a) 1 represents the control group; 2 the experimental group; 3, the normal control group. Ras: upstream activating protein of mitogen-activated protein kinases (MAPKs); C-Raf, P-A-Raf, P-B-Raf, P-C-Raf: Ser/Thr protein kinase of 40-75kD; P-Mekl/2: dual specificity protein kinase; P-Erkl/2: extracellular regulation protein kinase