Table 2 Summary of evidences for Pharmacological Treatment of FGIDs
From: Pharmacological interventions on early functional gastrointestinal disorders
FGID | Results |
|---|---|
Infant regurgitation | Alginate may be considered if symptoms are severe, associated with marked distress, and other non-pharmacological measures failed |
Infant rumination syndrome | No evidence of pharmacological treatment |
Cyclic vomiting syndrome | No RCTs. Retrospective studies showed benefit using cyproheptadine, propanolol and pizotifen in prophylaxis. During the acute phase of vomiting, intravenous infusion of glucoelctrolytic solutions, ondasetron, lorazepam and acid inhibitors are suggested. |
Infant colic | No evidence of pharmacological treatment |
Functional diarrhea | No evidence of pharmacological treatment |
Infant dyschezia | No evidence of pharmacological treatment |
Constipation | Lactulose is recommended for infants younger than 6Â months of age, whereas in older infants and in children PEG with or without electrolytes represents the first-line therapy for both fecal disimpaction and maintenance. |