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Table 1 Serology, clinical data and diagnosis confirmation of the ten ASD subjects with CD or positive CD serology

From: Serological screening for Celiac Disease in 382 pre-schoolers with Autism Spectrum Disorder

No. Age (months) Sex tTG Ig A (U/ml) EMA AGA IgA (U/ml) AGA IgG (U/ml) Risk factor and clinical presentation CD diagnosis
1 27 F >200.0 + 15.0 127.0 Inappetence MDB +
2 67 M 40.7 + 8.0 18.9 None MDB +
3 41 M 35.0 + 9.3 41.0 CD in the sister MDB +
4 44 M 102.0 + 1.4 1.1 None MDB +
5 24 F 11.6 - 0.2 6.4 Diarrhea MDB +
6 60 M >200 + 93.0 85.5 None HLA +
7 44 F 3.6 +/- 1.2 17.0 Growth failure DH
8 20 M 23.0 + 1.4 9.0 None n.p.
9 44 M 15.0 + 1.6 9.6 None n.p.
10a 58 F n.a. n.a. n.a. n.a. Growth failure Dental enamel defects MDB +, HLA +
  1. M male, F female, tTG Ig A anti-transglutaminase antibodies, EMA anti-endomysium antibodies, AGA IgA and IgG: anti-gliadin antibodies; cut -off values for tTG IgA, AGA IgA and AGA IgG: positive: > 10U/ml; borderline: 7–10 U/ml, negative: <7 U/ml; EMA: “+”: positive result; “-“: negative result; “+/-“: doubt result; n.p. not performed, n.a. not available, HLA+ human leukocyte antigen positivity, MDB + multiple duodenal biopsies positivitym, DH Duhring Dermatitis Herpetiformis
  2. aASD patient who had received a CD diagnosis before the hospitalization in our ASD Unit and for which serological data are not available