Table 1 Demographics of the study population

Gestational age (weeks)

median (IQR)

34.0 (31.0–37.0)

31.0

(27.0–36.0)

33.0

(31.0–35.0)

35.0

(34.0–38.0)

<.0001

Gestational age (weeks)

<.0001

24–29 N (%)

86 (20.4)

59 (45.0)

25 (16.7)

2 (1.4)

30–32 N (%)

76 (18.0)

19 (14.5)

45 (30.0)

12 (8.5)

33–36 N (%)

150 (35.6)

22 (16.8)

57 (38.0)

71 (50.4)

37–42 N (%)

110 (26.1)

31 (23.7)

23 (15.3)

56 (39.7)

Gestational age (weeks)

≤32 N (%)

162 (38.4)

78 (59.5)

70 (46.7)

14 (9.9)

< .0001

Birth weight (g)

median (IQR)

1921

(1368–2739)

1600

(896–2550)

1878

(1367–2430)

2295

(1835–3130)

<.0001

Sex

male N (%)

226 (53.6)

82 (62.6)

77 (51.3)

67 (47.5)

0.0356

Born in same hospital as NICU, n (%)

345 (81.8)

93 (71.0)

133 (88.7)

119 (84.4)

0.0004

Type of delivery

Caesarean, n(%)

300 (71.1)

96 (73.3)

119 (79.3)

85 (60.3)

0.0013

Age at admission (h)

median (IQR)

0.4 (0–3.3)

0.5 (0–3.2)

0.2 (0–0.6)

0.5 (0–19.1)

0.0017

CRIB score

median (IQR)

0 (0–1)

2 (1–5)

0 (0–1)

0 (0–1)

<.0001

APGAR score at 5 min

Median (IQR)

9 (8–10)

7 (6–9)

8 (8–9)

10 (9–10)

<.0001

Intubated on admission, n (%)

79 (18.7)

79 (60.3)

NA

NA

NA

Duration of IV (hours)

median (IQR)

NA

71.7

(16.8–157.0)

NA

NA

NA

Duration of NIV (hours)

median (IQR)

NA

N = 101

120

(33.0–262.8)

N = 150

36.1

(16.9–113.2)

NA

NA

Status at discharge

Dead, n (%)

14 (3.3)

12 (9.2)

1 (0.7)

1 (0.7)

<.0001

Days of participation in trial

median (IQR)

15 (7–28)

28 (13–28)

17 (8–28)

9 (5–15)

0.0001

Days of hospitalization

median (IQR)

15 (7–28)

25 (13–47)

17.0 (8–28)

8.5 (5–15)

<.0001