Lung structure and function similarities between primary ciliary dyskinesia and mild cystic fibrosis: a pilot study

Table 3 Lung imaging and lung function of PCD and CF patients controlled for diagnostic delay

	MRI			CT
	PCD	CF	p	PCD	CF	p
Severity of bronchiectasis	1.6 ± 0.2	1.6 ± 0.2	0.9	1.7 ± 0.2	1.6 ± 0.2	0.9
Severity of peribronchial wall thickening	1.7 ± 0.2	1.5 ± 0.2	0.4	1.8 ± 0.1	1.7 ± 0.1	0.4
Extent of bronchiectasis	1.8 ± 0.2	2.2 ± 0.2	0.3	1.8 ± 0.2	2.3 ± 0.2	0.3
Extent of mucous plugging	1.6 ± 0.2	1.3 ± 0.3	0.4	1.6 ± 0.3	1.5 ± 0.3	0.5
Extent of sacculations or abscesses	0.02 ± 0.04	0.03 ± 0.04	0.2	0.02 ± 0.04	0.03 ± 0.04	0.2
Generation of bronchial divisions involved (bronchiectasis or plugging)	2.8 ± 0.2	2.7 ± 0.2	0.1	2.8 ± 0.2	2.6 ± 0.2	0.1
Severity of bullae	0	0	–	0.1 ± 0.1	0.1 ± 0.1	0.1
Severity of emphysema	0.08 ± 0.05	0.03 ± 0.06	0.2	0.06 ± 0.05	0.04 ± 0.06	0.1
Severity of collapse or consolidations	1.5 ± 0.2	0.8 ± 0.2	<0.001	1.5 ± 0.2	0.8 ± 0.2	<0.001
Total score	11.0 ± 0.9	10.1 ± 0.9	0.1	11.4 ± 0.9	10.4 ± 0.9	0.1
Lung function	PCD		CF		p
FVC (Z-score)	−0.3 ± 0.3		−0.5 ± 0.3		0.08
FEV₁ (Z-score)	−1.4 ± 0.4		−1.4 ± 0.4		0.1
FEF_25–75 (Z-score)	−2.0 ± 0.4		−1.8 ± 0.4		0.4
FEV₁/FVC (Z-score)	−1.7 ± 0.3		−1.4 ± 0.3		0.5

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