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Table 2 VKDB prophylaxis strategies in various countries

From: Vitamin K deficiency: a case report and review of current guidelines

Country Years Studied Oral Vitamin K dosing regimen Incidence of Late VKDB per 100,000 Infants (95% CI)
Netherlands 1992-1994 1 mg at birth; 25 μg daily for 13 wk. 0 (0 to 0.7)
since 2005 1 mg at birth; 25 μg daily for 13 wk. 3.2 (1.2 to 6.9)
Germany 1993-1994 3 × 1 mg (days 1, 4-10, and 28-42) 1.3 (0.8 to 2.0)
1995-1998 3 × 2 mg (days 1, 4-10, and 28-42) 0.4 (0.2 to 0.7)
1997-2000 3 × 2 mg (days 1, 4-10, and 28-42) 0.8 (0.4 to 1.4)
1997-2001 3 × 2 mg (days 1, 4-10, and 28-42) 0.44 (0.2 to 0.9)
France / 2 mg weekly for 6 mo no date available
Australia 1993-1994 3 × 1 mg (days 1, 3-5, and 21-28) 1.5 (0.5 to 3.6)
Denmark 1992-2000 2 mg at birth; 1 mg weekly for 3 mo 0 (0 to 0.9)
since 2000 2 mg im at birth no date available
Switzerland 1995-2002 2 × 2 mg (h 4, day 4) 1.2 (0 to 6.5)
since 2003 3 × 2 mg (h 4, day 4, week 4) 0,87 (0.24 to 2.24)
United Kingdom / 1 mg im at birth; 3 × 1 mg po (day 1, week 1, week 4) 0.1
/ 3 × 2 mg po (day 1, week 1, week 4) 0.43
Canada / 1 mg im at birth 0.37
United States / 1 mg im at birth no date available
Italy / various schemes no date available