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Table 1 Overview of ocular features in mucopolysaccharidoses (MPS)

From: Ocular features in mucopolysaccharidosis: diagnosis and treatment

  Ocular manifestations
MPS type Corneal clouding Retinopathy Glaucoma Optic nerve abnormalities Other
MPS I-S (Scheie) + ++ + +  
MPS I-HS (Hurler-Scheie) ++ ++ ++ ++  
MPS I-H (Hurler) +++ + + ++ +  
MPS II (Hunter) + + + + ++  
MPS III (Sanfilippo) + + + + + + Bushy eyebrows, late blindness
MPS IV (Morquio) + + + + + Pseudoexophthalmos
MPS VI (Maroteaux-Lamy) +++ Unknown ++ ++  
MPS VII (Sly) ++ Unknown ++ ++ Colobomas of the iris
MPS IX (Natowicz) Unknown Unknown Unknown Unknown  
  1. Modified from [25]
  2. + mild, ++ moderate, +++ severe