Table 1 The functions and pathways enriched for the up-regulated genes
From: Genomics of neonatal sepsis: has-miR-150 targeting BCL11B functions in disease progression
Category | Description | P-value | Gene number |
|---|---|---|---|
BP | GO:0071222~cellular response to lipopolysaccharide | 3.05E-06 | 10 |
GO:0051384~response to glucocorticoid | 1.75E-05 | 8 | |
GO:0006955~immune response | 6.59E-05 | 14 | |
GO:0045766~positive regulation of angiogenesis | 1.31E-04 | 8 | |
GO:0045087~innate immune response | 3.22E-04 | 22 | |
CC | GO:0070062~extracellular exosome | 3.26E-06 | 51 |
GO:0005615~extracellular space | 3.15E-05 | 29 | |
GO:0005886~plasma membrane | 1.58E-04 | 59 | |
GO:0016020~membrane | 2.03E-03 | 32 | |
GO:0031093~platelet alpha granule lumen | 1.08E-02 | 4 | |
MF | GO:0035035~histone acetyltransferase binding | 2.54E-03 | 4 |
GO:0001077~transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 9.14E-03 | 8 | |
GO:0002020~protease binding | 1.40E-02 | 5 | |
GO:0016787~hydrolase activity | 1.56E-02 | 5 | |
GO:0019899~enzyme binding | 1.88E-02 | 9 | |
Pathway | hsa04668:TNF signaling pathway | 3.65E-06 | 10 |
hsa05150:Staphylococcus aureus infection | 3.23E-04 | 6 | |
hsa05142:Chagas disease (American trypanosomiasis) | 7.74E-03 | 6 | |
hsa04380:Osteoclast differentiation | 1.90E-02 | 6 | |
hsa04910:Insulin signaling pathway | 2.39E-02 | 6 |