Table 2 The functions and pathways enriched for the down-regulated genes
From: Genomics of neonatal sepsis: has-miR-150 targeting BCL11B functions in disease progression
Category | Description | P-value | Gene number |
|---|---|---|---|
BP | GO:0050776~regulation of immune response | 4.11E-15 | 15 |
GO:0007166~cell surface receptor signaling pathway | 2.56E-06 | 11 | |
GO:0050852~T cell receptor signaling pathway | 8.71E-05 | 7 | |
GO:0072678~T cell migration | 3.56E-04 | 3 | |
GO:0045059~positive thymic T cell selection | 8.47E-04 | 3 | |
CC | GO:0042101~T cell receptor complex | 1.22E-10 | 7 |
GO:0005886~plasma membrane | 1.40E-04 | 35 | |
GO:0042105~alpha-beta T cell receptor complex | 2.26E-04 | 3 | |
GO:0001772~immunological synapse | 5.25E-04 | 4 | |
GO:0009897~external side of plasma membrane | 4.83E-03 | 6 | |
MF | GO:0004888~transmembrane signaling receptor activity | 4.20E-06 | 9 |
GO:1990405~protein antigen binding | 4.46E-04 | 3 | |
GO:0030246~carbohydrate binding | 1.62E-03 | 6 | |
GO:0023024~MHC class I protein complex binding | 1.40E-02 | 2 | |
GO:0032393~MHC class I receptor activity | 2.31E-02 | 2 | |
Pathway | hsa04660:T cell receptor signaling pathway | 4.90E-07 | 8 |
hsa04672:Intestinal immune network for IgA production | 7.58E-05 | 5 | |
hsa05340:Primary immunodeficiency | 5.41E-04 | 4 | |
hsa04514:Cell adhesion molecules (CAMs) | 5.95E-04 | 6 | |
hsa04650:Natural killer cell mediated cytotoxicity | 2.80E-03 | 5 |