Table 1 Precautions, indications and contraindications of DPT

Contraindications

• SCAR, Serum Sickness-Like Reactions, internal organ or system involvement.

• Availability of alternative drugs, the drug will be probably not used in the future.

• Suggestive clinical history, positive allergy tests.

• Active disease such as uncontrolled asthma, urticaria, intercurrent infections, severe allergic rhinitis. Conditions that may affect treatment of allergic reactions, such as cardiovascular disease, treatment with β-blockers.

Precautions

• The risk/benefit balance must be discussed with patient and caregivers in children with anaphylaxis.

Indications

• Mild reactions.

• Suggestive clinical history with negative or unavailable allergy tests.

• Clinical history not suggestive and/or non-specific symptoms.

• To exclude cross-reactivity with related drugs in subjects with known drug reaction.