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Table 6 Comparison of growth parameters between/among subgroups of important associated variablesa

From: Postnatal length and weight growth velocities according to Fenton reference and their associated perinatal factors in healthy late preterm infants during birth to term-corrected age: an observational study

 

PMA at birth

Sex

Number of fetus

Intrauterine growth status

34 weeks (N = 99)

35 weeks (N = 173)

36 weeks (N = 327)

Female(N = 262)

Male(N = 337)

Singleton(N = 449)

Twin (N = 150)

SGA (N = 30)

AGA (N = 546)

LGA (N = 23)

PMA at birth

–

–

–

35.34 ± 0.77

35.42 ± 0.74

35.39 ± 0.75

35.34 ± 0.75

35.43 ± 0.73

35.37 ± 0.76

35.65 ± 0.65

Male, N(%)

51 (51.5)

95 (54.9)

191 (58.4)

–

–

266 (59.2)

71 (47.3)κ

21 (70.0)

304 (55.7)

12 (52.2)

Twin, N(%)

25 (25.3)

49 (28.3)

76 (23.2)

79 (30.2)

71 (21.1)ε

–

–

11 (36.7)

139 (25.5)

0 (0)Æ­Æž

SGA, N(%)

4 (4.0)

9 (5.2)

17 (5.2)

9 (3.4)

21 (6.2)

19 (4.2)

11 (7.3)

–

–

–

AGA, N(%)

93 (93.9)

160 (92.5)

293 (89.6)

242 (92.4)

304 (90.2)

407 (90.6)

139 (92.7)

–

–

–

LGA, N(%)

2 (2.0)

4 (2.3)

17 (5.2)

11 (4.2)

12 (3.6)

23 (5.1)

0 (0)κ

–

–

–

Maternal age

29.72 ± 3.26

30.93 ± 4.13*

30.72 ± 4.02*

30.76 ± 3.95

30.50 ± 3.96

30.62 ± 4.15

30.59 ± 3.29

29.00 ± 2.48

30.59 ± 3.95ƭ

33.35 ± 4.21ƭƞ

Birth Length(cm)

45.59 ± 2.14

46.93 ± 1.96*

48.09 ± 1.94*§

47.14 ± 2.13

47.50 ± 2.22ε

47.54 ± 2.24

46.75 ± 1.90κ

44.55 ± 2.32

47.36 ± 2.00ƭ

50.44 ± 1.53ƭƞ

Birth Weight(kg)

2.29 ± 0.32

2.51 ± 0.36*

2.78 ± 0.40*§

2.56 ± 0.41

2.67 ± 0.42ε

2.67 ± 0.44

2.47 ± 0.32κ

1.95 ± 0.25

2.61 ± 0.33ƭ

3.73 ± 0.36ƭƞ

Birth LengthZ

0.22 ± 0.84

0.27 ± 0.78

0.26 ± 0.79

0.35 ± 0.75

0.18 ± 0.82ε

0.32 ± 0.80

0.05 ± 0.76κ

−0.93 ± 0.83

0.27 ± 0.72ƭ

1.38 ± 0.58ƭƞ

Birth WeightZ

−0.07 ± 0.78

−0.12 ± 0.82

−0.04 ± 0.88

−0.03 ± 0.84

−0.09 ± 0.85

0.03 ± 0.88

− 0.37 ± 0.67κ

−1.73 ± 0.44

−0.07 ± 0.63ƭ

2.19 ± 0.61ƭƞ

PMA at visit(week)

40.00 ± 0.70

40.67 ± 0.73*

41.19 ± 0.91*§

40.78 ± 0.96

40.89 ± 0.92

40.86 ± 0.94

40.79 ± 0.92

40.85 ± 0.92

40.84 ± 0.94

40.81 ± 0.90

Term-corrected Length(cm)

51.54 ± 1.95

52.60 ± 2.11*

53.51 ± 2.19*§

52.41 ± 2.17

53.32 ± 2.23ε

53.08 ± 2.33

52.46 ± 1.90κ

50.41 ± 2.09

52.95 ± 2.13ƭ

55.64 ± 1.71ƭƞ

Term-corrected Weight (kg)

3.72 ± 0.54

3.94 ± 0.55*

4.18 ± 0.59*§

3.88 ± 0.58

4.15 ± 0.58ε

4.08 ± 0.62

3.89 ± 0.49κ

3.29 ± 0.59

4.03 ± 0.54ƭ

5.03 ± 0.44ƭƞ

Term-corrected LengthZ

0.27 ± 0.91

0.46 ± 0.89

0.67 ± 0.90*§

0.54 ± 0.89

0.55 ± 0.92

0.59 ± 0.95

0.39 ± 0.78κ

−0.62 ± 0.82

0.55 ± 0.85

1.78 ± 0.68

Term-corrected WeightZ

0.35 ± 1.03

0.47 ± 0.96

0.70 ± 0.99*§

0.49 ± 0.96

0.65 ± 1.02

0.64 ± 1.04

0.38 ± 0.82κ

−0.98 ± 1.02

0.59 ± 0.86ƭ

2.34 ± 0.64ƭƞ

ΔLengthZ

0.04 ± 0.90

0.20 ± 0.86

0.41 ± 0.75*§

0.19 ± 0.83

0.36 ± 0.80ε

0.27 ± 0.82

0.34 ± 0.82

0.30 ± 0.76

0.28 ± 0.82

0.40 ± 0.92

ΔWeightZ

0.42 ± 0.77

0.58 ± 0.74

0.74 ± 0.68*§

0.52 ± 0.70

0.74 ± 0.72ε

0.61 ± 0.75

0.75 ± 0.61κ

0.75 ± 0.84

0.66 ± 0.71

0.15 ± 0.60ƭƞ

Adjusted ΔLengthZ#

0.10(−0.07, 0.27)

0.22 (0.10, 0.34)

0.38 (0.29, 0.47)*§

0.20(0.10, 0.30)

0.35 (0.27, 0.44)ε

0.26 (0.19, 0.34)

0.36(0.23, 0.49)

0.23(−0.06, 0.52)

0.28 (0.22, 0.35)

0.45 (0.11, 0.78)

Adjusted ΔWeightZ#

0.55 (0.41, 0.70)

0.60 (0.50, 0.71)

0.70 (0.62, 0.78)

0.53 (0.45, 0.62)

0.73 (0.66, 0.81)ε

0.61 (0.54, 0.67)

0.76 (0.65, 0.87)κ

0.70 (0.45, 0.95)

0.66 (0.60, 0.72)

0.18(−0.11, 0.46)ƭƞ

  1. #Adjusted ΔLengthZ and adjusted ΔWeightZ was ΔLengthZ and ΔWeightZ adjusted for respective associated variables by analysis of covariance(for example, ΔLengthZ of different PMA at birth subgroups(34, 35 and 36 weeks PMA at birth) was adjusted for Sex, PMA at visit and Maternal age; ΔWeightZ of different PMA at birth subgroups was adjusted for Sex, PMA at visit, Number of fetus and Intrauterine growth status), other variables were compared by T test, chi-square test, analysis of variance
  2. *:Compared with 34 weeks PMA at birth subgroup, P < 0.05; §: compared with 35 week PMA at birth subgroup, P < 0.05; ε: compared with female subgroup, P < 0.05; κ: compared with singleton subgroup, P < 0.05; ƭ: compared with SGA subgroup, P < 0.05; ƞ: compared with AGA subgroup, P < 0.05
  3. aAbbreviations: PMA Postmenstrual age, SGA Small-for-gestational-age, AGA appropriate-for-gestational-age, LGA Large-for-gestational-age, LengthZ Z-score of Length calculated by Fenton reference, WeightZ Z-score of weight calculated by Fenton reference, ΔLengthZ Z-score change of length, ΔWeightZ, Z-score change of weight