Table 1 Baseline demographic and clinical characteristics of study population
nAnRC n = 805 (76.7%) | CA n = 61 (5.8%) | RC n = 184 (17.5%) | p-value | |
|---|---|---|---|---|
Female, n (%) | 390 (48.45) | 29 (47.54) | 104 (56.52) | 0.133 |
Age, mean (SD) | 12.06 (0.74) | 11.90 (0.62) | 12.18 (0.74) | 0.025 |
Height, mean (SD) | 152.58 (7.87) | 151.52 (7.81) | 153.51 (7.41) | 0.168 |
Weight, mean (SD) | 49.05 (12.07) | 50.11 (12.65) | 50.28 (13.52) | 0.417 |
BMI (kg/m2), mean (SD) | 20.92 (4.28) | 21.62 (4.15) | 21.16 (4.78) | 0.426 |
Skin Prick Test +, n (%) (#) | 274 (34.16) | 43 (70.49) | 76 (41.30) | < 0.001 |
Environmental exposure current | ||||
Tobacco smoke, n (%) | 440 (54.93) | 27 (44.26) | 107 (58.15) | 0.167 |
Traffic in the zone of residence, n (%) | 627 (77.99) | 41 (67.21) | 134 (72.83) | 0.071 |
Mould/dampness, n (%) | 108 (13.47) | 7 (11.67) | 31 (17.03) | 0.396 |
Spirometric values* | ||||
FEV1%predicted, mean (SD) | 100.39 (11.80) | 96.96 (12.68) | 98.82 (11.34) | 0.035 |
FEV1 Z, mean (SD) | 0.04 (1.02) | −0.26 (1.09) | −0.09 (0.98) | 0.037 |
FVC %predicted, mean (SD) | 97.10 (13.29) | 97.60 (13.63) | 95.51 (12.44) | 0.304 |
FVC Z, mean (SD) | −0.27 (1.14) | −0.22 (1.17) | − 0.40 (1.07) | 0.314 |
FEV1/FVC % predicted, mean (SD) | 103.28 (7.57) | 99.17 (8.11) | 103.33 (7.89) | < 0.001 |
FEV1/FVC Z, mean (SD) | 0.60 (1.21) | −0.04 (1.20) | 0.60 (1.25) | < 0.001 |
FEF25–75%predicted, mean (SD) | 102.10 (22.19) | 89.17 (21.67) | 101.76 (23.98) | < 0.001 |
FEF25–75 Z, mean (SD) | 0.05 (0.98) | −0.55 (1.02) | 0.02 (1.05) | < 0.001 |