From: Preterm birth: seven-year retrospective study in a single centre population
Characteristics | Controls (n = 7315) | Preterm Cases (n = 639) | p-value | |
---|---|---|---|---|
Maternal age (years), mean (SD) | 31.87 (6.04) | 31.68 (5.65) | 0.025 | |
Pre-pregnancy weight (kg), mean (SD) | 63.44 (13.98) | 63.73 (13.32) | 0.2 | |
Maternal BMI, n (%) | Underweight | 293 (4) | 102 (16) | < 0.0001* |
Normal | 4462 (61) | 262 (41) | ||
Overweight | 1682 (23) | 51 (8) | ||
Obesity | 878 (12) | 224 (35) | ||
Marital status, n (%) | Married | 5998 (82) | 492 (77) | 0.003* |
Unmarried | 1317 (18) | 147 (23) | ||
Parity | Nulliparous | 4096 (56) | 367 (57.5) | 0.5 |
Parous | 3219 (44) | 272 (42.5) | ||
Prior history of PTB, Yes/No, n (%) | 256/7059 (3.5/96.5) | 40/428 (8.5/91.5) | < 0.0001* | |
Treatment for cervical dysplasia | ||||
Yes/No, n (%) | 110/ 7205 (1.5/98.5) | 13/626 (2/98) | 0.2 | |
Cervical Length (mm), median (IQR) | 38 (34–42) | 31 (23–37) | < 0.0001* | |
Uterine Anomalies, Yes/No, n (%) | 66/7249 (0.9/99.1) | 22/617 (3.4/96.6) | < 0.0001* | |
Vaginal/Urinary Infections Yes/No, n (%) | 1463/5852 (20/80) | 115/524 (18/82) | 0.02* | |
Poly/oligohydramnios | ||||
Yes/No, n (%) | No | 7096 (97) | 518 (81) | < 0.0001* |
Polyhydramnios | 37 (0.5) | 13 (2) | ||
Oligohydramnios | 182 (2.5) | 102 (9) | ||
Hypertension, Yes/No, n (%) | 366/6949 (5/95) | 115/524 (18/82) | < 0.0001* | |
Thyroid disease, Yes/No, n (%) | 1024/6291 (14/86) | 83/556 (13/87) | 0.5 | |
Diabetes, Yes/No, n (%) | 732/6583 (10/90) | 93/546 (14.5/85.5) | 0.004* | |
Maternal Surgery, Yes/No, n (%) | 2677/4638 (36.6/63.4) | 252/387 (39.5/60.5) | 0.2 | |
Psychological Disorders, Yes/No, n (%) | 37/7278 (0.5/99.5) | 7/632 (1.1/98.9) | 0.3 | |
Smoking, Yes/No, n (%) | 658/6657 (9/91) | 51/588 (8/92) | 0.5 |