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Fig. 4 | Italian Journal of Pediatrics

Fig. 4

From: The role of miR-29c/B7-H3/Th17 axis in children with Mycoplasma pneumoniae pneumonia

Fig. 4

B7-H3 is the target of miR-29c confirmed by luciferase reporter assay. a The binding site of miR-29c in the 3’UTR of the B7-H3 mRNA and the mutant sequence of 3’UTR of B7-H3 mRNA. b Luciferase activity in THP-1 cells transiently cotransfected with pLenti-miR-29c or empty vector and B7-H3–3’UTR reporter plasmid or B7-H3–3’UTR-Mut reporter plasmid. Data are shown as mean ± SEM of 3 independent experiments

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