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Table 1 Possible situations for referring children with cancer to a PPC specialista

From: A consensus conference report on defining the eligibility criteria for pediatric palliative care in Italy

On diagnosis

During the illness

Child with a new life-threatening illness diagnosis

Treatment-resistant disease

Extended intrinsic brainstem glioma

Progressive disease (e.g., new metastases)

Stage IV neuroblastoma

Relapsed disease after remission

Solid metastatic tumour

Resistant or recurrent disease after hematopoietic stem cell transplantation

Any other type of tumour with an event-free survival (EFS) prediction of < 40% with current therapies

Exposure to life-threatening complications (e.g., organ failure, prolonged intubation)

New diagnosis with difficult pain management or other symptoms

Development of new and significant toxicity related to treatment and/or psychosocial stress

Prolonged hospitalisation (over 3 weeks) without evidence of clinical improvement

Prolonged admission to intensive care (over 1 week) without evidence of clinical improvement

  1. aminimal mod. from Kaye E, Rubenstein J, Levine D, Baker J, Dabbs D, Friebert S20