Table 2 Summary of the studies reporting the effects of Lactobacillus reuteri for the treatment of Infant Colic
Author and year | Intervention | Control | Treatment duration | Follow up | Type of feeding |
|---|---|---|---|---|---|
Savino F et al. 2010 [96] | Lactobacillus reuteri DSM 17938 108 CFU (5 drops) | Placebo (identical formulation but without live bacteria) | 21 days | No follow up | Exclusive breast-feeding |
Szajewska H et al. 2013 [64] | Lactobacillus reuteri DSM 17938 108 CFU (5 drops) | Placebo (identical formulation but without live bacteria) | 21 days | 8 days | Exclusive or predominat (> 50%) breast-feeding |
Chau K et al. 2015 [97] | Lactobacillus reuteri DSM 17938 108 CFU (5 drops) | Placebo (same excipient ingredients but without live bacteria) | 21 days | No follow up | Exclusive breast-feeding |
Sung V et al. 2014 [98] | Lactobacillus reuteri DSM 17938 108 CFU (5 drops) | Placebo (maltodextrin in the same oil suspension) | 1 month | 5 months | Formula feeding, breast feeding |