Patient and reference | Age (y/m), Gender (M/F) | CSF Gram Stain and culture positivization | CSF analysis at presentation | Therapy and duration | Time of hydrocephalus development | Neurosurgical management | Outcome |
---|---|---|---|---|---|---|---|
1 present case | 0 y, 11 m F | Gram stain positive Bacillus culture positive at day 2 | WBC 300/mm3 Glu 8; Pr 91 | Ampicillin 26 days, Gentamicin 15 days + TMP/SMX 15 days | - 10 days | EVD and VPS | Discharged after 40 days Persistence of right eye palsy |
2 Xiaotang [16] | 3 y, 3 m F | NA | WBC 162/mm3, Glu and Pr unknown | Meropenem + Amikacina 3 days, Ampicillin + Meropenem 15 days | Unknown | Unknown | Discharge unknown Hearing lesion; development delay |
3 Ben Shimol [17] | 6 y, 0 m F | Gram stain unknown; culture positive on day 7 | WBC 150/mm3 (N 65%); Glu 43; Pr 38 | Ampicillin 28 days + gentamicin 12 days | - 9 days | EVD | Discharged after 34 days No sequelae |
4 Montejo [18] | 0 y,8 m F | Gram stain unknown; culture positive on day 3 | WBC 240/mm3 (N 80%); Glu 35; Pr 57 | Ampicillin + gentamicin 21 days | - 8 days | EVD and VPS | Discharged after unknown days Strabismus left eye. |
5 Lee [19] | 7 y, 0 m F | Gram stain negative on day 1; Gram stain positive Cocci on day 3 | WBC 1500/mm3 (N 30%); Glu 25; Pr 117 | Vancomycin + gentamicin+ ampicillin for unknown days | - 10 days | EVD | Discharged after 61 days No sequelae |
6 Platnaris [20] | 0 y, 7 m M | Gram stain negative on day 1; culture positive on day 3 | WBC 2550/mm3 (N 80%); Glu 53; Pr 128,5 | Gentamicin 14 days+ Ampicillin 21 days. | - 10 days | EVD | Discharged after 30 days No sequelae |
7 Flodrops [21] | 7 y, 0 m F | Gram stain negative on day 1; Culture positive on day 11 | WBC 160/mm3 (N 5%); Glu 58; Pr 266 | Vancomycin 8 days + amoxicillin 21 days | - 11 days | EVD | Discharged after unknown days No sequelae |
8 Ulloa-Gutierrez [22] | 3 y, 6 m M | Gram stain negative on day 1; Gram positive Cocci on day 3 | WBC 755/mm3 (N 95%); Glu 21; Pr 266 | Ampicillin + gentamicin 1 day until death | - 5 days | EVD | Death on day 4 |
9 Ulloa- Gutierrez [22] | 6 y, 6 m M | Gram stain positive Coccobacilli on day 1; Culture positive on day 5 | WBC 800/mm3 (N 60%); Glu 32; Pr 79 | Ampicillin + gentamicin 3 days until death | - 7 days | EVD | Death on day 7 |
10 Ulloa- Gutierrez [22] | 10 y, 0 m F | Negative Gram stain on day 1; Culture negative. Negative Gram stain on day 3; Culture positive on day 5 | WBC 6000/mm3 (N 80%); Glu 62; Pr 121 | Meropenem 22 days + Amikacin 10 days + Rifampin 14 days | - 8 days | EVD | Discharged after 28 days Upper left arm tremor and adiadochokynesis. |