Variable |  | Group 1 | Previous 5 yearsa | P |
---|---|---|---|---|
Population number | 37 | 89 | – | |
Chronological age at B2 (as referred by parents or family pediatrician) | 6.86 ± 0.61 | 7.22 ± 0.48 | p < 0.005 | |
Chronological age at diagnosis (yr) | 7.11 ± 0.72 | 7.53 ± 0.50 | p < 0.0005 | |
Time from B2 to diagnosis (months) | 3.1 ± 0.9 | 3.0 ± 0.8 | P = NS | |
Height, SDS | 0.84 ± 1.32 | 0.79 ± 1.44 | P = NS | |
BMI, SDS | 0.83 ± 0.91 | 0.68 ± 0.88 | P = NS | |
Tanner stage at diagnosis (percentage) | ||||
 II | 43.8 | 55.5 |  | |
 III | 53,1 | 38.8 | p < 0.05 | |
 IV | 3.1 | 5.4 |  | |
 V | – | – |  | |
Bone age (yr) | 9.40 ± 1.10 | 9.60 ± 1.20 | p = NS | |
Bone age minus chronological age (yr) | 2.29 ± 0.38 | 2.07 ± 0.70 | P = NS | |
Basal LH, IU/L | 1.2 ± 0.7 | 0.8 ± 0.6 | p < 0.005 | |
Basal FHS, IU/L | 1.9 ± 1.7 | 2.2 ± 1.3 | p = NS | |
Peak LH at GnRH stimulation, IU/L | 11.9 ± 4.2 | 9.4 ± 4.0 | p < 0.005 | |
Basal estradiol (females only), pmol/L | 129.9 ± 18.7 | 117.6 ± 19.2 | p < 0.005 | |
Uterine length, cm | 4.42 ± 0.43 | 3.99 ± 0.47 | p < 0.0005 | |
Ovarian volume, cm3 | 3.32 ± 0.42 | 2.83 ± 0.46 | p < 0.0005 | |
Electronic device use (h) | 3.9 ± 1.5 | – | – |