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Table 2 Characteristics of Children with Graves’ Disease after Treatment

From: Effects of glucocorticoid pulse therapy on thyroid function and thyroid antibodies in children with graves’ disease

Characteristic

The pulse group (N = 20)

The control group (N = 20)

P value

Palpitations (%)

3 (15.0)

1 (5.0)

0.292

Fatigue (%)

3 (15.0)

2 (10.0)

0.633

Irritability (%)

8 (40.0)

10 (50.0)

0.525

Increased appetite (%)

17 (85.0)

1 (5.0)

< 0.001*

Weight loss (%)

0 (0)

0 (0)

1.000

Diarrhoea (%)

1 (5.0)

2 (10.0)

0.548

Increased perspiration (%)

8 (40.0)

5 (25.0)

0.311

Exophthalmos (mm)

17.73 ± 3.92

18.18 ± 4.25

0.730

Heart rate (bpm)

90 ± 8

87 ± 9

0.341

Systolic blood pressure (mmHg)

100 ± 7

98 ± 5

0.426

Diastolic blood pressure (mmHg)

64 ± 3

65 ± 4

0.661

TPOAb(+) (%)

15 (75.0)

16 (80.0)

0.705

TGAb(+) (%)

8 (40.0)

15 (75.0)

0.025*

TRAb(+) (%)

20 (100.0)

18 (90.0)

0.147

  1. Data are presented as means±SD, median (interquartile range), or number (percentage)
  2. No change occurred in exophthalmos and thyroid goiter after 60 days of treatment
  3. Abbreviations: TPOAb thyroid peroxidase antibodies, TGAb thyroglobulin antibodies, TRAb thyroid stimulating hormone receptor antibodies
  4. *P < 0.05