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Table 3 differential diagnosis of BACM

From: Management and outcome of benign acute childhood myositis in pediatric emergency department

Guillain-Barrè syndrome

Symptoms onset 2–4 weeks after viral illness

Distal paresthesiaand ascending paralysis

Symmetric weakness with absent/decreased/preserved deep tendon reflexes

Normal or slightly increased serum CK

Dermatomyositis

Subtle onset and chronic course

Proximal muscle weakness

Skin involvement

Muscular dystrophy

Muscle weakness

Chronic persistent increase of CK levels

Possible family history of neuromuscular conditions

Juvenile Idiopathic arthritis

Asymmetric distribution with swelling and tenderness in joints

Subacute onset

Normal CK levels

Transient synovitis of the hip

Symptoms onset 2–3 weeks after viral illness

Asymmetric pain and limited motion of the hip

Normal CK levels

Osteomyelitis

Frequent hystory of trauma or penetration of the skin

Elevation of inflammatory markers

Swelling of soft tissues in affected area with or without erythema

Myalgia associated to Influenza

Less severe

Concomitant with viral symptoms

Normal CK levels