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Table 6 Treatment outcomes in patients with stroke

From: Treating the symptom or treating the disease in neonatal seizures: a systematic review of the literature

Population

First-line AED

Response to first-line AED

Response to Lidocaine as a 2nd−/3rd-line AED

Response to Midazolam

as a 2nd−/3rd-line AED

Response to other AEDs

45 newborns with stroke

45 (100%) phenobarbital

4 (5%) did not require further treatment

27 out of 32 (84%) patients treated with lidocaine responded (higher in full-term newborns and when used as a 2nd-line AED)

5 out of 32 (16%) patients treated with midazolam responded

1 patient responded to levetiracetam as a 3rd-line AED