Table 1 Clinical characteristics of the 51 children who underwent haploidentical hematopoietic stem cell transplantation
Characteristic | Value |
|---|---|
Age at HID-HSCT (years), median (range) | 8 (1.1–18) |
Gender, n (%) | |
 Female | 12 (23.5%) |
 Male | 39 (76.5%) |
Primary disease, n (%) | |
 Acute lymphoblastic leukemia | 14 (27.4%) |
 Acute myeloid leukemia | 25 (49.0%) |
 Myelodysplastic syndrome-secondary acute myeloid leukemia | 4 (7.9%) |
 Advanced myelodysplastic syndrome | 2 (3.9%) |
 Acquired severe aplastic anemia | 6 (11.8%) |
aRemission status, n (%) | |
 First complete remission (CR1) | 24 (55.8%) |
 Second complete remission (CR2) | 5 (11.6%) |
 Not in remission | 14 (32.6%) |
Relationship of donor to recipient, n (%) | |
 Parent | 49 (96.1%) |
 Sibling | 2 (3.9%) |
ABO blood type match between donor and recipient, n (%) | |
 Matched | 30 (58.8%) |
 Mismatched | 21 (41.2%) |
Donor-recipient gender, n (%) | |
 Male-male | 18 (35.3%) |
 Male-female | 9 (17.6%) |
 Female-female | 3 (5.9%) |
 Female-male | 21 (41.2%) |
Time to engraftment (days), median (range) | |
 Neutrophils | 12 (10–22) |
 Thrombocytes | 13 (7–35) |
Number of CD34+ cells infused (× 106/kg), median (range) | 5.33 (2.3–28) |
Follow-up time (days), median (range) | 405 (44–1432) |