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Table 2 Descriptive characteristics of patients in Groups CF NBS and Group CF

From: Impact of newborn screening for cystic fibrosis on clinical outcomes of pediatric patients: 10 years’ experience in Lodz Voivodship

Investigated trait

Statistical parameters

Group CF NBS

(n = 27)

Group CF

(n = 52)

P-values

Body Weight in the 5th year of life (kg),

  

0.201

mean (SD), min.-max

18.30 (1.92), 15.00–21.00

17.77 (2.43), 14.50–23.00

median (Q1-Q3), min.-max.

19 (17–20), 15.00–21.00

17 (16–20), 14.50–23.00

Body Weight in the 8th year of life (kg),

  

0.312

mean (SD), min.-max

25.27 (1.85), 22.00–28.00

25.11 (4.60), 19.00–38.00

median (Q1-Q3), min.-max.

25 (24–27), 22.00–28.00

24.50 (21–27), 19.00–38.00

Absolute weight gain 5–8 years (kg),

  

0.777

mean (SE), min.-max.

6.57 (0.46), 3.00–11.50

7.23 (0.48), 2.50–15.00

median (Q1-Q3), min.-max.

6.50 (5–8), 3.00–11,.50

6.00 (5–8), 2.50–15.00

Date of CF diagnosis (month of life),

  

< 0.001

mean (SD), min.-max.

1.59 (0.9), 2.7

45.25 (47.77), 1–180

median (Q1-Q3), min.-max.

2 (2–3), 2–7

34.50 (6–66), 1–180

Infection of PA in the 5th year, n (%)

7 (26.92)

17 (40.48)

0.256

Infection of PA in the 8th year, n (%)

10 (50.00)

27 (58.70)

0.513

Infection of MRSA in the 5th year, n (%)

6 (22.22)

13 (30.23)

0.463

Number of exacerbation in 5–8 years,

  

< 0.001

mean (SD), min.-max.

4.20 (2.50), 2–9

6.77 (3.18), 2–14

median (Q1-Q3), min.-max.

3 (2–5), 2–9

6 (4–9), 2–14

Number of hospitalizations in 5–8 years,

  

< 0.001

mean (SD), min.-max.

0.50 (0.61), 0–2

2.14 (1.82), 0–9

median (Q1-Q3), min.-max.

0 (0–1), 0–2

2 (1–3), 0–9

FEV1 in the 5th year (% of pred. value),

  

0.721

mean (SD), min.-max.

91.93 (10.22), 72–105

89.75 (17.12), 47–119

median (Q1-Q3), min.-max.

97 (82–99), 72–105

88 (81–105), 47–119

FEV1 in the 8th year (% of pred. value),

  

0.308

mean (SD), min.-max.

92.30 (13.49), 65–110

88.20 (20.64), 42–138

median (Q1-Q3), min.-max.

94 (83–104), 65–10

89 (77–98), 42–138

  1. (Abbreviations: n number; SD standard deviation; Q1 lower quartile; Q3 upper quartile; min. minimum value; max. maximum value)