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Table 2 Descriptive characteristics of patients in Groups CF NBS and Group CF

From: Impact of newborn screening for cystic fibrosis on clinical outcomes of pediatric patients: 10 years’ experience in Lodz Voivodship

Investigated trait Statistical parameters
Group CF NBS
(n = 27)
Group CF
(n = 52)
P-values
Body Weight in the 5th year of life (kg),    0.201
mean (SD), min.-max 18.30 (1.92), 15.00–21.00 17.77 (2.43), 14.50–23.00
median (Q1-Q3), min.-max. 19 (17–20), 15.00–21.00 17 (16–20), 14.50–23.00
Body Weight in the 8th year of life (kg),    0.312
mean (SD), min.-max 25.27 (1.85), 22.00–28.00 25.11 (4.60), 19.00–38.00
median (Q1-Q3), min.-max. 25 (24–27), 22.00–28.00 24.50 (21–27), 19.00–38.00
Absolute weight gain 5–8 years (kg),    0.777
mean (SE), min.-max. 6.57 (0.46), 3.00–11.50 7.23 (0.48), 2.50–15.00
median (Q1-Q3), min.-max. 6.50 (5–8), 3.00–11,.50 6.00 (5–8), 2.50–15.00
Date of CF diagnosis (month of life),    < 0.001
mean (SD), min.-max. 1.59 (0.9), 2.7 45.25 (47.77), 1–180
median (Q1-Q3), min.-max. 2 (2–3), 2–7 34.50 (6–66), 1–180
Infection of PA in the 5th year, n (%) 7 (26.92) 17 (40.48) 0.256
Infection of PA in the 8th year, n (%) 10 (50.00) 27 (58.70) 0.513
Infection of MRSA in the 5th year, n (%) 6 (22.22) 13 (30.23) 0.463
Number of exacerbation in 5–8 years,    < 0.001
mean (SD), min.-max. 4.20 (2.50), 2–9 6.77 (3.18), 2–14
median (Q1-Q3), min.-max. 3 (2–5), 2–9 6 (4–9), 2–14
Number of hospitalizations in 5–8 years,    < 0.001
mean (SD), min.-max. 0.50 (0.61), 0–2 2.14 (1.82), 0–9
median (Q1-Q3), min.-max. 0 (0–1), 0–2 2 (1–3), 0–9
FEV1 in the 5th year (% of pred. value),    0.721
mean (SD), min.-max. 91.93 (10.22), 72–105 89.75 (17.12), 47–119
median (Q1-Q3), min.-max. 97 (82–99), 72–105 88 (81–105), 47–119
FEV1 in the 8th year (% of pred. value),    0.308
mean (SD), min.-max. 92.30 (13.49), 65–110 88.20 (20.64), 42–138
median (Q1-Q3), min.-max. 94 (83–104), 65–10 89 (77–98), 42–138
  1. (Abbreviations: n number; SD standard deviation; Q1 lower quartile; Q3 upper quartile; min. minimum value; max. maximum value)