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Table 3 Univariate analysis for Risk factors of ICU admission

From: Age-specific risk factors of severe pneumonia among pediatric patients hospitalized with community-acquired pneumonia

 

ICU Admission

No ICU Admission

OR(95% CI)

P

Age n(%)

 < 6 m

1949 (69.02)

7342 (42.32)

0.62 [0.59–0.64]

< 0.0001

 6 m-1y

319 (11.30)

3200 (18.44)

 

 1y-2y

282 (9.99)

3027 (17.45)

 

 2y-6y

274 (9.70)

3781 (21.79)

 

Gender (male) n(%)

1878 (66.50)

11,287 (65.05)

1.07 [0.98–1.16]

0.1343

Rural resident n(%)

1467 (51.98)

5625 (32.59)

2.24 [2.07–2.43]

< 0.0001

Premature birth n(%)

658 (24.38)

1480 (8.64)

3.41 [3.08–3.78]

< 0.0001

LBW n(%)

659 (23.98)

1339 (7.86)

3.70 [3.33–4.10]

< 0.0001

Unhealthy parents

340 (12.26)

1250 (7.28)

1.78 [1.57–2.02]

< 0.0001

Feeding

 Breastfeeding

1083 (39.22)

9035 (52.73)

1.45 [1.38–1.52]

< 0.0001

 Mixture

934 (33.83)

5103 (29.78)

 

 Formula

744 (26.95)

2997 (17.49)

 

CHD

1095 (38.77)

1634 (9.42)

6.09 [5.56–6.67]

< 0.0001

History of pneumonia

673 (23.83)

2112 (12.17)

2.26 [2.05–2.49]

< 0.0001

History of jaundice

207 (7.33)

444 (2.56)

3.01 [2.54–3.57]

< 0.0001

Symptoms at admission n(%)

 Cough

2145 (75.96)

15,762 (90.85)

0.32 [0.29–0.35]

< 0.0001

 Fever

885 (31.34)

7882 (45.43)

0.55 [0.50–0.60]

< 0.0001

 Wheezing

483 (17.10)

2479 (14.29)

1.24 [1.11–1.38]

< 0.0001

 Dyspnea

679 (24.04)

1588 (9.15)

28.38 [17.01–47.36]

< 0.0001

 Cyanosis

264 (9.35)

88 (0.51)

20.23 [15.84–25.84]

< 0.0001

Abnormal chest X-ray

461 (16.32)

459 (2.65)

8.26 [7.20–9.47]

< 0.0001

Abnormal results n(%)

 WBC

1318 (89.23)

7746 (80.76)

1.89 [1.62–2.21]

< 0.0001

 Neutrophils

762 (53.14)

2409 (25.24)

3.36 [3.00–3.76]

< 0.0001

 Lymphocytes

881 (61.44)

2781 (29.14)

3.87 [3.45–4.35]

< 0.0001

 Blood serum

487 (33.94)

990 (9.96)

4.64 [4.09–5.28]

< 0.0001

 CRP

542 (35.33)

2489 (27.17)

1.49 [1.34–1.66]

< 0.0001

 ESR

131 (70.43%)

1272 (82.38%)

0.51 [0.36–0.72]

0.0001

 ALB

173 (11.70)

296 (2.96)

9.14 [7.89–10.58]

< 0.0001

 ALT

149 (10.37)

352 (3.53)

3.16 [2.59–3.86]

< 0.0001

 AST

189 (13.13)

393 (3.94)

3.68 [3.07–4.43]

< 0.0001

 TBIL

372 (25.89)

1047 (10.51)

2.98 [2.60–3.40]

< 0.0001

 SCR

44 (3.07%)

139 (1.40%)

2.23 [1.58–3.14]

< 0.0001

 Proteinuria

442 (33.01)

1105 (14.15)

2.92 [2.58–3.31]

< 0.0001

 RSV

160 (25.56)

319 (20.05)

1.53 [1.24–1.87]

0.0046

  1. Definition of abnormal laboratory results: WBC count < 5.0*10^9/L or > 15*10^9/L for 1 m–6 m, < 6.0*10^9/L or > 17.5*10^9/L for 6 m–12 m, < 1.0*10^9/L or > 8.5*10^9/L for 1y-6y; neutrophil count < 1.0*10^9/L or > 5*10^9/L for 1 m–6 m, < 1.0*10^9/L or > 8.5*10^9/L for 6 m-6y; lymphocytes count < 4.0*10^9/L or > 10*10^9/L for 1 m–6 m, < 4.0*10^9/L or > 12*10^9/L for 6 m–12 m, < 1.5*10^9/L or > 9.5*10^9/L for 1y-6y; blood serum, < 135 or 145 mmol/L; CRP > 6 mg/L; ESR > 10 mm/h; ALB< 35 g/L; ALT > 100 U/L; AST > 100 U/L; TBIL>17umol/L
  2. CAP Community-acquired pneumonia, ICU Intensive care unit, LBW Low birth weight (birth weight < 2.5Kg); Unhealthy parents, at least one parent has health condition, CHD Congenital heart disease, WBC White blood cell, Neu Neutrophil count, Lym Lymphocyte count, Na Serum sodium, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, ALB Albumin, AST Aspartate aminotransferase, ALT Alanine aminotransferase (ALT), TBIL Total bilirubin (TBIL), SCR Serum creatine, RSV Respiratory syncytial virus
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Italian Journal of Pediatrics

ISSN: 1824-7288

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