Table 2 Parameter estimate for the base model without the addition of covariates
Parameter | Mean estimate of the final model ± SE |
|---|---|
Central volume (Vc) (L) | 2.01 ± 0.023 |
Peripheral colume (Vp) (L) | 3.32 ± 0.28 |
Clearance (CL) (L/h) | 1.15 ± 0.022 |
Intercompartmenral clearance (Q) (L/h) | 0.75 ± 0.044 |
Between subject variability associated with Vc (%) | 105% |
Between subject variability associated with CL (%) | 60% |
Shrinkage Eta Vd | 0.22 |
Shrinkage Eta Cl | 0.066 |
Additional error (mg/L) | 0.28 |