Table 1 Epidemiological data, etiologic factors and clinical features in 208 children with IgAV
Demographic characteristics of the cohort | n = 208 | % of the cohort |
|---|---|---|
Mean age (years), (Range) | 6.44 (0–18) | |
Males | 108 | 51 |
Female | 100 | 49 |
Ratio M:F | 1.08:1 | |
Seasonal pattern | ||
Spring-summer | 63 | 30 |
Autumn-winter | 145 | 70 |
Possible etiological factors | ||
Total | 132 | 63 |
Identified | 59 | 28 |
Group A beta hemolytic streptococcus | 40 | 19 |
Adenovirus | 9 | 4 |
Mycoplasma | 5 | 2 |
Coxsackievirus | 2 | 1 |
Respiratory Syncytial Virus | 2 | 1 |
Epstein Barr Virus | 1 | 0.5 |
Symptoms | ||
Purpura | 208 | 100 |
Diffuse | 117 | 56 |
Leg and buttocks | 23 | 11 |
Arthritis | 48 | 23 |
Major joints | 44 | 22 |
Minor joints | 29 | 14 |
Abdominal pain | 52 | 25 |
GI complications | 7 | 4 |
Thickening of the bowel wall | 3 | 2 |
Peritoneal effusion | 2 | 1 |
Intussusception | 2 | 1 |
Renal involvement | 58 | 28 |
Proteinuria | 41 | 20 |
Hematuria | 38 | 18 |
Both | 21 | 10 |
Mesangial IgA deposits | 3 | 1 |
Scrotal involvement | 7 | 4 |
Cardiovascular involvement | 5 | 3 |
Mild ECG alterations | 2 | |
Cardiac abnormalities | 3 | |
Pulmonary complications | 1 | 0.5 |