Variables | Without NEC (n = 66) | With NEC (n = 20) | p value |
---|---|---|---|
Maternal characteristics | |||
 Maternal age (years) | 34.14 ± 4.36 | 33.90 ± 5.12 | 0.857* |
Mother’s education | 0.134 | ||
 High, n (%) | 3 (4.5) | 2 (10) | |
 Intermediate, n (%) | 52 (78.8) | 16 (80) | |
 Low, n (%) | 11 (16.7) | 2 (10) | |
GDM (%) | 7 (10.6) | 0 (0) | 0.193 |
PIH (%) | 9 (13.6) | 3 (15) | 0.100 |
PPROM (%) | 34 (51.5) | 6 (30) | 0.126 |
Histologic chorioamnionitis (%) | 33 (50.0) | 11 (55.0) | 0.909 |
Neonatal characteristics | |||
 Gestational age (weeks) | 28.88 ± 2.65 | 27.03 ± 3.04 | 0.026* |
 Birth weight (g) | 1202.20 ± 256.40 | 985.50 ± 305.62 | 0.008 |
 Cesarean section (%) | 52 (78.8) | 18 (90) | 0.340 |
 Male sex (%) | 35 (53) | 12 (60) | 0.618 |
 Apgar score at 1 min | 3.52 ± 1.69 | 2.70 ± 1.42 | 0.034* |
 Apgar score at 5 min | 6.42 ± 1.19 | 5.35 ± 1.42 | 0.001* |
 Antenatal corticosteroid (%) | 47 (71.2) | 16 (80.0) | 0.569 |
 Postnatal corticosteroid (%) | 14 (21.2) | 4 (20.0) | 1.000 |
 RDS (%) | 57 (86.4) | 20 (100) | 0.109 |
 Culture proven sepsis (%) | 31 (47.0) | 14 (70) | 0.126 |
 Hypotension (%) | 4 (6.1) | 2 (10) | 0.620 |
 Severe NEC (Bell stage ≧ 3) (%) | 0 | 3 (15) | 0.011 |
 PDA (%) | 39 (59.1) | 16 (80) | 0.114 |
 BPD moderate and severe (%) | 14 (21.2) | 5 (25) | 0.762 |
 ROP (%) | 30 (45.5) | 10 (50) | 0.377 |
 TPN days | 32.98 ± 26.94 | 52.00 ± 28.58 | 0.003* |
Infants characteristics on PMA at MRI | |||
 PMA at MRI (weeks) | 36.91 ± 1.71 | 37.90 ± 2.45 | 0.210* |
 Weight at MRI (g) | 2515.91 ± 514.12 | 2517.00 ± 730.57 | 0.368* |
 Height at MRI (cm) | 45.97 ± 3.41 (n = 65) | 45.93 ± 4.04 | 0.697* |
 Head circumference at MRI (cm) | 33.18 ± 1.82 | 32.88 ± 1.67 | 0.380* |