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Table 4 Developmental assessment of preterm infants at 18 months of corrected age*

From: Altered microstructure of the splenium of corpus callosum is associated with neurodevelopmental impairment in preterm infants with necrotizing enterocolitis

Variables Cognitive impairment Language impairment Motor impairment
Odds ratio (95% C.I) p value Odds ratio (95% C.I) p value Odds ratio (95% C.I) p value
NEC 1.95 (0.20–18.79) 0.561 1.50 (0.29–7.59) 0.622 58.26 (7.80–435.12) < 0.001
GA (weeks) 0.92 (0.59–1.43) 0.726 0.85 (0.62–1.17) 0.321 1.20 (0.85–1.70) 0.290
PMA at MRI (weeks) 1.11 (0.69–1.85) 0.649 1.23 (0.87–1.76) 0.238 0.98 (0.65–1.47) 0.932
Sex (Male) 8.25 (0.57–57.30) 0.137 1.78 (0.45–7.04) 0.411 2.57 (0.54–12.25) 0.236
BPD moderate and severe 1.78 (0.12–25.60) 0.184 10.43 (0.75–144.1) 0.080 0.23 (0.01–2.92) 0.262
Maternal education** 0.49 (0.04–5.81) 0.572 0.53 (0.08–3.21) 0.491 2.87 (0.26–31.21) 0.387
  1. Abbreviations: C. I, confidence interval; NEC, necrotizing enterocolitis; GA, gestational age; PMA, postmenstrual age; MRI, magnetic resonance imaging; BPD, bronchopulmonary dysplasia
  2. *Includes 75 preterm infants (19 with NEC, 56 without NEC) out of 86 preterm infants
  3. **Defined as mothers with college graduate or higher educational level