Table 5 Determinants of HIV infection among children born to HIV positive mothers on PMTCT at referral hospitals in west Amhara, Ethiopia, 2021
Variables | Child HIV Status | COR (95% CI) | AOR (95% CI) | |
|---|---|---|---|---|
Positive | Negative | |||
Place of delivery | ||||
 Home | 40 | 36 | 9.3 (5.0, 14.0) | 4.3 (2.0, 9.6) ** |
 Health Institution | 26 | 218 | 1 | |
Place of residence | ||||
 Rural | 30 | 55 | 3.0 (1.7, 5.3) |  |
 Urban | 36 | 199 | 1 | |
ANC visit | ||||
 No | 22 | 16 | 7.437 (2.4, 8.40) |  |
 Yes | 44 | 238 | 1 | |
Mode of delivery | ||||
 Vaginal Delivery | 60 | 211 | 2.0 (1.8, 5.0) |  |
 Cesarean Delivery | 6 | 43 | 1 | |
Breast feeding practice in the first six weeks | ||||
 Mixed feeding | 26 | 27 | 5.5 (2.9, 10.0) | 10 (3.2, 17.9) *** |
 EBF/ERF | 40 | 227 | 1 | |
Immunization status of the infant | ||||
 Non immunized | 27 | 24 | 6.6 (3.5, 12.6) |  |
 Immunized | 39 | 230 | 1 | |
ARV prophylaxis for the infant at birth | ||||
 Not given | 41 | 20 | 19.2 (6.8, 27.7) |  |
 Given | 25 | 234 | 1 | |
Infant’s nevirapine adherence | ||||
 Poor | 40 | 14 | 26.4 (9.7, 34.8) | 10 (3.2, 22.4) *** |
 Good | 26 | 240 | 1 | |
Maternal ARV adherence | ||||
 Poor | 37 | 15 | 20.3 (9.9, 23.1) | 4.3 (1.4,13.4) ** |
 Good | 29 | 239 | 1 | |
Nutritional status of the mother | ||||
 Malnourished | 22 | 3 | 41.8 (12, 145) |  |
 Not malnourished | 44 | 251 | 1 | |
Mother’s WHO clinical stage at enrollment | ||||
 WHO Stage > 1 | 45 | 29 | 16.6 (8.7, 21.7) | 11.4 (4.1,19.1) *** |
 WHO Stage 1 | 21 | 225 | 1 | |
Mother’s CD4 count at enrollment | ||||
 CD4 </= 350 | 33 | 36 | 6.0 (3.3, 11.0) |  |
 CD4 > 350 | 33 | 218 | 1 | |
Age of the infant at enrollment | ||||
 Enrolled < 6 weeks | 32 | 12 | 18.9 (6.9, 29.4) | 15.0 (3.0, 20.5) ** |
 Enrolled = < 6 weeks | 34 | 242 | 1 | |
Birth weight at delivery in grams | ||||
 Birth weight < 2500 | 26 | 23 | 6.5 (3.4, 12.5) |  |
 Birthweight > = 2500 | 40 | 231 | 1 | |