Skip to main content

Table 1 Comparisons major cytokines related with regulation the bone resorption between patients with Thalassemia major and healthy controls

From: Assessment of biochemical bone markers of osteoporosis in children with thalassemia major

  β -TM group
(n = 38)
Control group
(n = 40)
P
Age (y)
(mean ± SD)
12.92 ± 3.10 12.50 ± 3.12 t = −  0.596
p = 0.553
DPD (nM/mM Kr)
(mean ± SD)
44.57 ± 24.14 51.29 ± 31.06 t = 1.069
p = 0.289
Beta-CTx (pg/mL)
(mean ± SD)
1025.76 ± 439.71 968.00 ± 388.46 t = −  0.614
P = 0.541
OPG (pmol/L)
(mean ± SD)
2.01 ± 0.66 2.43 ± 0.57 t = 3.027
p = 0.003
RANKL (pmol/L)
(mean ± SD)
346.18 ± 142.63 318.05 ± 110.75 t = − 0.976
p = 0.332
RANKL/OPG 46.09 33.24 p = 0.012
  1. DPD Deoxypyridinoline, OPG Osteoprotegerin, RANKL Receptor activator of NF-κB ligand, β –TM Beta-thalassemia, Beta-CTx Beta-Crosslaps