Table 1 Comparisons major cytokines related with regulation the bone resorption between patients with Thalassemia major and healthy controls
From: Assessment of biochemical bone markers of osteoporosis in children with thalassemia major
β -TM group (n = 38) | Control group (n = 40) | P | |
|---|---|---|---|
Age (y) (mean ± SD) | 12.92 ± 3.10 | 12.50 ± 3.12 | t = − 0.596 p = 0.553 |
DPD (nM/mM Kr) (mean ± SD) | 44.57 ± 24.14 | 51.29 ± 31.06 | t = 1.069 p = 0.289 |
Beta-CTx (pg/mL) (mean ± SD) | 1025.76 ± 439.71 | 968.00 ± 388.46 | t = − 0.614 P = 0.541 |
OPG (pmol/L) (mean ± SD) | 2.01 ± 0.66 | 2.43 ± 0.57 | t = 3.027 p = 0.003 |
RANKL (pmol/L) (mean ± SD) | 346.18 ± 142.63 | 318.05 ± 110.75 | t = − 0.976 p = 0.332 |
RANKL/OPG | 46.09 | 33.24 | p = 0.012 |