Table 2 Neonatal outcomes in twins according to delivery indications
Spontaneous n: 165 | pPROM n: 128 | Indicated n: 232 | No indicated n: 152 | Total (n 677) | P | |
|---|---|---|---|---|---|---|
Male | 92 (55.8) | 52 (40.6) | 120 (51.7) | 71 (46.7) | 335 (49.5) | 0.06* |
Mean birth weight | 2352 (±334) | 2355 (±383) | 2257 (±359) | 2349 (±375) | 2319 (±363) | 0.6§ |
Stillbirth | 1 (0.6) | 1 (0.8) | 4 (1.6) | 1 (0.7) | 7 (1%) | 0.8** |
Weight percentile | ||||||
AGA | 146 (88.5) | 112 (87.5) | 174 (75) | 121 (79.6) | 553 (81.7) | < 0.01** |
LGA | 3 (1.8) | 3 (2.3) | 2 (0.9) | 4 (2.6) | 12 (1.8) | |
SGA | 16 (9.7) | 13 (10.3) | 56 (24.1) | 27 (17.8) | 112 (16.5) | |
Median NICU length of stay | 6 (3–8) | 5 (3–8) | 5 (3–10) | 4 (3–7) | 5 (3–8) | < 0.06+ |
NICU stay longer than 5 days | 101 (61.2) | 73 (57) | 140 (60.3.) | 72 (47.4) | 386 (57) | < 0.05* |
Metabolic acidosis at birth | 8 (4.8) | 5 (3.9) | 6 (2.4) | 0 | 19 (2.8) | 0.02** |
5′ Apgar score < 3 | 0 | 1 (0.8) | 0 | 0 | 1 (0.1) | 0.2** |
Cardiopulmonary resuscitation | 8 (4.8) | 5 (3.9) | 6 (2.4) | 0 | 19 (2.8) | 0.02** |
Respiratory support | ||||||
No support | 140 (84.8) | 108 (84.4) | 192 (82.8) | 131 (86.2) | 571 (84.3) | 0.7** |
Invasive | 3 (1.8) | 1 (0.8) | 2 (0.8) | 0 | 6 (0.9) | |
Non invasive | 22 (13.4) | 19 (14.8) | 38 (16.4) | 21 (13.8) | 100 (14.8) | |
Seizures | 0 | 1 (0.8) | 0 | 0 | 1 (0.1) | 0.2** |
Therapeutic hypothermia | 0 | 1 (0.8) | 0 | 0 | 1 (0.1) | 0.2** |
Jaundice | 38 (23) | 21 (16) | 40 (17.2) | 21 (13.8) | 120 (17.3) | 0.2* |
Sepsis | 7 (4.2) | 8 (6.2) | 5 (2) | 2 (1.3) | 22 (3.2) | 0.08** |
Antibiotic therapy | 10 (6.1) | 12 (9.4) | 10 (4) | 3 (2.2) | 35 (5.2) | 0.04** |
Hypoglycemia | 41 (25.1) | 30 (23.4) | 57 (24.7) | 35 (23.8) | 163 (24.4) | 0.9* |
Difficulty feeding | 17 (10.3) | 23 (18) | 32 (13.8) | 17 (11.2) | 89 (13.1) | 0.2* |
Cerebral lesions | ||||||
None | 157 (95.1) | 122 (95.3) | 229 (98.7) | 151 (99.3) | 659 (97.3) | < 0.01** |
Stroke | 0 | 0 | 0 | 0 | 0 | |
Basal nuclei anomalies | 8 (4.9) | 6 (4.7) | 3 (1.3) | 0 | 17 (2.5) | |
IVH > =2 | 0 | 0 | 0 | 1 (0.7) | 1 (0.2) | |
Congenital anomalies | ||||||
None | 152 (92.1) | 123 (96.1) | 214 (92.2) | 144 (94.8) | 633 (93.5) | 0.5** |
Cardio vascular | 7 (4.2) | 5 (3.9) | 11 (4.7) | 6 (4) | 29 (4.3) | |
CNS | 1 (0.7) | 0 | 0 0 | 1 (0.6) | 2 (0.3) | |
Gastrointestinal | 0 | 0 | 2 (0.9) | 0 | 2 (0.3) | |
Genito-urinary | 5 (3) | 0 | 5 (2.2) | 1 (0.6) | 11 (1.6) | |
Pregnancies with at least one infant affected by the Adverse Composite Neonatal Outcome | 58 (72.5) | 43 (68.2) | 79 (70.5) | 46 (62.2) | 226 (68.7) | 0.5* |