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Table 2 Univariable and multivariable logistic regression models of factors associated with elevated ADA in hospitalized patients

From: Diversity of adenosine deaminase in children with EBV-related diseases

Variable

Model 1

 

Model 2

 

Model 3

 
 

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

ALT(U/L)

1.001 (1.000-1.002)

0.001

1.001 (1.001-1.002)

< 0.001

1.001 (1.001-1.002)

< 0.001

EBV-DNA

10.895 (8.746-13.572)

< 0.001

11.702 (9.368-14.617)

< 0.001

8.486 (6.753-10.663)

< 0.001

Diseases

 Inflammatory disease

4.339 (3.580-5.257)

< 0.001

4.402 (3.625-5.345)

< 0.001

3.915 (3.198-4.794)

< 0.001

 Malignant disease

1.265 (1.017-1.572)

0.035

1.357 (1.088-1.694)

0.007

1.381 (1.101-1.734)

0.005

 Autoimmune disease

2.202 (1.754-2.766)

< 0.001

2.155 (1.713-2.711)

< 0.001

2.307 (1.823-2.920)

< 0.001

 Other diseases

1(reference)

 

1(reference)

 

1(reference)

 
  1. Abbreviations: ADA Adenosine deaminase, ALT Alanine aminotransferase, OR Odds ratio, CI Confidence interval, EBV Epstein-Barr virus. Model 1 was not adjusted. Model 2 was adjusted for age and gender. Model 3 was adjusted as Model 2 + ALT, EBV-DNA positive, diseases