Table 3 Endocrine profile and/or brain (hypothalamic-pituitary region) MRI anomalies of present patient compared to those reported in literature
Present patient | Jedraszak G et al., 2015 [13] Patient 1 | Jedraszak G et al., 2015 [13] Patient 2 | Melo C et al., 2013 [12] | Matsumoto R et al., 2005 [14] | Masukawa H et al., 1998 [15] | Pierson M et al., 1975 [16] | |
|---|---|---|---|---|---|---|---|
Hormonal defects | GH and cortisol deficiencies, hypothyroidism | GH deficiency | GH deficiency | GH deficiency | Hypogonadotropic hypogonadism | Hypogonadotropic hypogonadism | GH deficiency |
Hypothalamic and pituitary gland MRI anomalies | Aplasia of the anterior pituitary gland, agenesis of the stalk and ectopic neurohypophysis | Small intrasellar anterior pituitary gland and ectopic neurohypophysis located in the postero-superior region of the pituitary stalk | Hypotrophic intrasellar anterior pituitary gland and ectopic neurohypophysis | Hyperintense focus at the infundibular region of neurohypophysis corresponding to an ectopic posterior pituitary lobe | No abnormalities | No abnormalities | No abnormalities |