Table 1 Characteristics of included studies (Part 1)
UDCA supplementation group (UDCA + phototherapy) | Control group (phototherapy only) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
No | Author | Number of participants | Mean age (SD) | Female (n) | Weight (g) | TSB (mg/dL) | Therapy | Number of participants | Mean age (SD) | Female (n) | Weight (g) | TSB (mg/dL) |
1 | Akefi [25] | 110 | 5.3 (2.9) | 62 | – | 16.8 (2.4) | UDCA 10 mg/kg/d | 110 | 4.9 (2.1) | 52 | – | 15.7 (2.5) |
2 | El-Gendy [26] | 50 | 4,9 (1.44) | 20 | – | 16.5 (1.51) | UDCA 1* | 50 | 4.86 (1.6) | 24 | – | 16.4 (1.57) |
3 | Gharehbaghi [27] | 80 (A = 40, B = 40) | A = 5.91 (2.49), B = 5.1 (2.47) | A = 18, B = 16 | A = 3175.41 (561.53), B = 2961.71 (440.03) | A = 19.88 (2.33), B = 19.33 (2.51) | A = UDCA 1* B = UDCA 2* | 40 | 5.91 (2.49) | 18 | 3192.91 (431.02) | 19.76 (2.64) |
4 | Hassan [28] | 100 | 5.4 (1.4) | 44 | 3.2 (0.4) (in kg) | 16.3 (1.7) | UDCA 1* | 100 | 5.3 (1.5) | 49 | 3.1 (0.4) (in kg) | 16.5 (2.9) |
5 | Honar [21] | 40 | 3.7 (1) | 21 | 2970 (292) | 15.9 (1.7) | UDCA 1* | 40 | 3.6 (1) | 22 | 2985 (312) | 16.3 (1.5) |
6 | Jafari [29] | 64 (A = 32, B = 32) | – | – | – | A = 16.47 (1.65), B = 16.22 (1.67) | A = UDCA 1* B = UDCA 3* | 32 | – | – | – | 16.64 (1.72) |
7 | Meena [30] | 50 | – | 19 | 2.73 (0.23) | 16.33 (1.58) | UDCA 1* | 50 | – | 17 | 2.69 (0.41) | 15.6 (2.78) |
8 | Shahramian [31] | 100 | – | 47 | – | – | UDCA 2* | 100 | – | 48 | – | – |