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Table 3 Independent risk factors for neonatal moderate or severe HIE based on logistic regression analysis

From: Maternal and neonatal exposure to risk factors for neonates with moderate or severe hypoxic ischemic encephalopathy: a cross-sectional study

Variable

Model 1a

Model 2b

Unadjusted OR(95%CI)

P-value

Adjusted OR(95%CI)

P-value

Birth weight(g)

 1500–2499

1.701(1.153 ~ 3.082)

0.019

1.965(1.086 ~ 4.127)

0.036

 2500–4000

1.00(ref)*

1.00(ref)

 > 4000

2.879(0.234 ~ 4.328)

3.212(0.597 ~ 5.161)

Gestational age at birth(weeks)

 32–36

1.152(1.067 ~ 2.985)

0.027

1.557(1.589 ~ 4.862)

0.041

 37–42

1.00(ref)

1.00(ref)

 > 42

2.983(0.719 ~ 5.106)

3.027(0.165 ~ 6.017)

1-min Apgar’s score

 ≥ 7

1.00(ref)

 < 0.001

1.00(ref)

0.009

 < 7

4.253(3.592 ~ 6.315)

5.618(3.724 ~ 7.353)

Intrauterine distress

Yes

5.921(3.565 ~ 6.828)

0.002

4.916(3.431 ~ 7.398)

0.011

No

1.00(ref)

1.00(ref)

Amniotic fluid contamination

 Yes

2.775(1.986 ~ 4.357)

 < 0.001

3.965(2.153 ~ 5.782)

0.025

 No

1.00(ref)

1.00(ref)

  1. aModel 1: the unadjusted ORs by each maternal and neonatal characteristic
  2. bModel 2: adjusted ORs for the different maternal and neonatal characteristics for each other
  3. *1.00(ref) meant the reference group