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Table 6 Treatment for bronchiolitis

From: UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants

Treatment

Indications

Evidence Quality Recommendation Strength

Supportive treatment

Recommended

Evidence Quality: A

Recommendation Strength: Strong

Oxygen therapy

Recommended (when SpO2<92%)

Evidence Quality: A

Recommendation Strength: Strong

HFNC

Recommended when standard subnasal supplemental O2 fails in infants who are hypoxic.

(It should not be used as a primary treatment modality)

Evidence Quality: B

Recommendation Strength: Moderate

Nebulized hypertonic saline solution

Not Recommended

Evidence Quality: B

Recommendation Strenght: Moderate

Inhaled bronchodilators

Not Recommended

Evidence Quality: B

Recommendation Strength: Strong

Chest physiotherapy

Not Recommended

Evidence Quality: A

Recommendation Strength: Moderate

Nebulized adrenaline

Not Recommended

Evidence Quality: B;

Recommendation Strength: Strong

Nebulized steroids

Not Recommended

Evidence Quality: A

Recommendation Strength: Strong

Systemic steroids

Not Recommended

Evidence Quality: A

Recommendation Strength: Strong

Antibiotics

Not Recommended

(Except in case of strong suspicion or clear evidence of a secondary bacterial infection)

Evidence Quality: B;

Recommendation Strength: Strong

Other

Antivirals

Montelukast

DNase

Inhaled furosemide

Inhaled ipratropium bromide

Magnesium sulfate

Helium

Surfactant

Methylxanthine

Not Recommended

Evidence Quality: B;

Recommendation Strength: Strong