From: UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants
Treatment | Indications | Evidence Quality Recommendation Strength |
---|---|---|
Supportive treatment | Recommended | Evidence Quality: A Recommendation Strength: Strong |
Oxygen therapy | Recommended (when SpO2<92%) | Evidence Quality: A Recommendation Strength: Strong |
HFNC | Recommended when standard subnasal supplemental O2 fails in infants who are hypoxic. (It should not be used as a primary treatment modality) | Evidence Quality: B Recommendation Strength: Moderate |
Nebulized hypertonic saline solution | Not Recommended | Evidence Quality: B Recommendation Strenght: Moderate |
Inhaled bronchodilators | Not Recommended | Evidence Quality: B Recommendation Strength: Strong |
Chest physiotherapy | Not Recommended | Evidence Quality: A Recommendation Strength: Moderate |
Nebulized adrenaline | Not Recommended | Evidence Quality: B; Recommendation Strength: Strong |
Nebulized steroids | Not Recommended | Evidence Quality: A Recommendation Strength: Strong |
Systemic steroids | Not Recommended | Evidence Quality: A Recommendation Strength: Strong |
Antibiotics | Not Recommended (Except in case of strong suspicion or clear evidence of a secondary bacterial infection) | Evidence Quality: B; Recommendation Strength: Strong |
Other Antivirals Montelukast DNase Inhaled furosemide Inhaled ipratropium bromide Magnesium sulfate Helium Surfactant Methylxanthine | Not Recommended | Evidence Quality: B; Recommendation Strength: Strong |