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Fig. 2 | Italian Journal of Pediatrics

Fig. 2

From: SIGIRR-caspase-8 signaling mediates endothelial apoptosis in Kawasaki disease

Fig. 2

Endothelial cell apoptosis in KD condition was associated with caspase-8 activation. A The apoptotic percentage of endothelial cells was analyzed using flow cytometry. The histogram was the quantitative analysis of Annexin V-FITC-positive cells. B-G The protein expression levels of SIGIRR, TLR4, cleaved caspase-8 and cleaved caspase-3, and BAX/Bcl-2 ratio were determined in the treated endothelial cells by Western blotting. Data were presented as mean ± SD (n = 3). * P < 0.05 versus HC group, and # P < 0.05 versus KD group

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