Table 2 Diagnostic time according to clinical features of EGID patients
Overall EGID patients | Diagnostic time (months) median (IQR)a | p-value |
Age at symptoms onset, years | 8 (3 – 11) | - |
≤ 1 year | 4.5 (1.5 – 10) | 0.04 (1 year vs. 12 years) |
1 – 5 years | 12 (1 – 15) | |
6 – 11 years | 24 (8 – 54) | |
≥ 12 years | 12 (12 – 30) | |
Age at diagnosis,years | 10 (6 – 13) | - |
Diagnostic time, months | 12 (12 –24) | - |
Eosinophilic esophagitis | Diagnostic time (months) median (IQR)a | p-value |
Sex | ||
Male | 12 (4.5 – 24) | 0.57 |
Female | 12 (3 – 22) | |
Age at symptoms onset, years | 8 (3 - 12) | - |
≤ 1 year | 3 (1 – 6) | n.s. |
1 – 5 years | 12 (1 – 17.5) | |
6 – 11 years | 12 (3.3 – 30) | |
≥ 12 years | 12 (12 – 30) | |
Age at diagnosis, years | 10 (4 – 14) | - |
Diagnostic time, months | 12 (4 – 24) | - |
Comorbidities | ||
Allergic diseases | ||
Yes | 12 (4 – 24) | 0.97 |
No | 17 (1.5 – 26) | |
Symptoms | ||
Dysphagia | ||
Yes | 12 (8 – 30) | 0.61 |
No | 12 (3 – 24) | |
Food impaction | ||
Yes | 18 (12 – 33) | 0.21 |
No | 12 (3 – 23) | |
Feeding issues and reduced appetite | ||
Yes | 24 (12 – 27) | 0.05 |
No | 12 (3 – 23) | |
Failure to thrive | ||
Yes | 25.5 (12 – 48) | 0.02 |
No | 12 (3.5 – 23.5) | |
GERD-like symptoms | ||
Yes | 12 (4.5 – 24) | 0.80 |
No | 12 (3 – 24) | |
Nausea and vomiting | ||
Yes | 8 (1 – 21) | 0.10 |
No | 12 (12 – 24) | |
Abdominal pain | ||
Yes | 12 (4 – 39) | 0.42 |
No | 12 (2 – 23) | |
Endoscopic pattern | ||
Fibro-stenotic patternb | ||
Yes | 12 (4 – 27) | 0.90 |
No | 12 (4 – 24) | |
Non-esophageal EGIDs | Diagnostic time (months) median (IQR)a | p-value |
Sex | ||
Male | 18 (12 – 82.5) | 0.31 |
Female | 12 (11 – 60) | |
Age at symptoms onset, years | 7 (3 – 11) | - |
≤ 1 year | 11 (11 – 11) | n.s. |
1 – 5 years | 12 (12 – 12) | |
6 – 11 years | 24 (12 – 78) | |
≥ 12 years | 12 (12 – 69) | |
Age at diagnosis, years | 11 (6.5 – 12) | - |
Diagnostic time, months | 12 (12 – 69) | - |
Comorbidities | ||
Allergic diseases | ||
Yes | 18 (12 – 69) | 0.87 |
No | 12 (12 – 69) | |
Symptoms | ||
Failure to thrive | ||
Yes | 90 (12 – 168) | 0.53 |
No | 12 (12 – 60) | |
Weight loss | ||
Yes | 12 (11 – 96) | 0.67 |
No | 18 (12 – 64.5) | |
Nausea and vomiting | ||
Yes | 24 (12 – 60) | 0.82 |
No | 12 (12 – 79.5) | |
Abdominal pain | ||
Yes | 12 (0 – 79.5) | 0.82 |
No | 24 (12 – 60) | |
Diarrhea | ||
Yes | 18 (12 – 51) | 0.92 |
No | 12 (12 – 90) | |