From: Paraneoplastic pemphigus and Castleman’s disease: a case report and a revision of the literature
Reference | Number of patients | Case number | Age (years) /sex | Personal history | Initial symptoms | Time to diagnosis | Mucosal manifestation | Skin manifestation | Systemic symptoms | Bronchiolitis obliterans |
---|---|---|---|---|---|---|---|---|---|---|
Index case | 1 | Index case | 13/F | No | Mucosal (oral) | 2 years | Oral Conjunctival | Blistering eruption | No | No |
Shu‐Ping Han et al. [7] | 1 | 1 | 13/F | No | Mucosal (oral) | 6 months | Oral | Lichen planus | No | Yes |
Mimouni et al. [8] | 1 | 2 | 9/M | No | Mucosal (Oral, Conjunctival) | 3 weeks | Oral Conjunctival | Blistering eruption Papular lichenoid rash Dystrophic nails | Dyspnea | Yes |
Choh NA et al. [9] | 1 | 3 | 16/M | No | Mucosal (oral) Skin Low grade fever | 1 month | Oral | Lichenoid rash | Fever | Yes |
Daneshpazhooh M et al. [10] | 1 | 4 | 10/F | Resection of cervical UCD (HV) 5 years before | Mucosal (oral, conjunctival) Skin | 2 months | Oral Conjunctival | Blistering eruption Papular lichenoid rash Dystrophic nails | Fever Dyspnea Cough | Yes |
Jindal T et al. [11] | 1 | 5 | 14/F | No | Mucosal (oral) | 5 months | Oral | No | No | Yes |
Koch LH et al. [12] | 1 | 6 | 14/F | No | Mucosal (Oral, Conjunctival, Genital) | 3 weeks | Oral Conjunctival Genital | Blistering eruption | No | Yes |
Jing L et al. [13] | 1 | 7 | 16/F | No | Mucosal (oral) | 3 months | Oral Conjunctival Genital | Blistering eruption | No | No |
Hung IJ et al. [14] | 1 | 8 | 14/M | No | Mucosal (oral) Skin Cough | 1 month | Oral Conjunctival Genital | Papular rash | Fever Cough | Yes |
Lane JE et al. [15] | 1 | 9 | 10/M | No | Mucosal (oral, conjunctival) Skin | 2 months | Oral Conjunctival Genital | Papular rash Dystrophic nails | Fever Cough Fatigue Constipation Weight loss (no food intake) | Yes |
Chin AC et al. [16] | 1 | 10 | 14/M | No | Mucosal (Oral, Conjunctival, Genital) | 3 months | Oral Conjunctival Genital | No | Dyspnea | Yes |
Nousari HC et al. [17] | 1 | 11 | 13/M | No | Mucosal (oral) | Not available | Oral Genital | Blistering eruption | No | Yes |
Lemon MA et al. [18] | 1 | 12 | 13/M | No | Epistaxis Mucosal (oral, conjunctival) | 1.5 months | Oral Conjunctival Genital | Maculopapular eruption Swollen nail folds Nails shedding | Weight loss (no food intake) | No |
Wang J et al. [19] | 2 | 13 14 | 17/M 17/F | Not available Not available | Mucosal (oral) Mucosal (oral) | 6 months 4 months | Oral Conjunctival Genital Oral Conjunctival Genital | Erythema multiform Lichen planus | Not available Not available | Yes Yes |
Kumar S et al. [20] | 1 | 15 | 15/M | No | Mucosal (oral) Abdominal pain | 3 months | Oral | No | Abdominal pain Weight loss (no food intake) | No |
Coulson IH et al. [21] | 1 | 16 | 17/F | No | Mucosal (oral) | 2 years | Oral Conjunctival Genital | Acral lichenoid eruption | Aseptic meningitis | Not available |
Velasco et al. [22] | 1 | 17 | 13/F | Not available | Mucosal (oral and conjunctival) | 3 months | Oral Conjunctival | No | Thyroid carcinoma | Yes |
Sathishkumar et al. [23] | 2 | 18 19 | 8/F 8/M | Not available Not available | Mucosal Mucosal | Not available Not available | Oral Conjunctival Genital Oral Conjunctival | Pemphigus vulgaris Lichen planus Pemphigus vulgaris Lichen planus Papular rash | Not available Not available | No No |
Reference | Case number | Form and Histological findings | Tumor localization | Tumor resection | Medication | outcome | Survival time |
---|---|---|---|---|---|---|---|
Index case | Index case | MCD (HV) | Retroperitoneal | No | Steroids Rituximab Siltuximab | Survive | Not available |
Shu‐Ping Han et al. [7] | 1 | UCD (HV-SR) | Retroperitoneal (Pararenal) | Yes, complete | oral methylprednisolone rituximab tocilizumab plasmapheresis Immunoglobulin (2 g/kg) | Survive | 12 months |
Mimouni et al. [8] | 2 | UCD (MX) | Retroperitoneal | Yes, complete | Prednisone Steroid Radiotherapy Rituximab Daclizumab | Survive | Not available |
Choh NA et al. [9] | 3 | UCD (HV) | Retroperitoneal | Yes, complete | Systemic and local steroids | Death (respiratory failure) | 1 month |
Daneshpazhooh M et al. [10] | 4 | UCD (HV) | Cervical | Yes, complete | Prednisone Azathioprine | Death (respiratory failure) | 2 months |
Jindal T et al. [11] | 5 | UCD (HV) | Chest (paratracheal area) | Yes, complete | Prednisone | Death (respiratory failure) | 4 months |
Koch LH et al. [12] | 6 | UCD (HV) | Retroperitoneal | Yes, complete | Prednisone Cyclophosphamide Thalidomide Tocilizumab | Survive | Not available |
Jing L et al. [13] | 7 | UCD (HV) | Retroperitoneal | Yes, complete | Prednisone Plasmapheresis | Survive | Not available |
Hung IJ et al. [14] | 8 | UCD (HV) | Chest (paratracheal region) | Yes, complete | Steroids | Death (respiratory failure) | 7 months |
Lane JE et al. [15] | 9 | UCD (HV) | Retroperitoneal | Yes, partial | Prednisone Immunoglobulin Cyclosporine Rituximab Daclizumab Radiotherapy | Death (respiratory failure) | 15 months |
Chin AC et al. [16] | 10 | UCD (HV) | Chest (Mediastinum) | Yes, complete | Prednisone Azathioprine Colchicine Thalidomide Embrel Cyclosporine Rapamycin Plasmapheresis Pirfenidone Living-related bilateral lung-lobe transplantation | Survive | Not available |
Nousari HC et al. [17] | 11 | UCD (HV) | Chest (Mediastinum) | Yes, complete | Prednisone Cyclosporine Plasmapheresis | Death (respiratory failure) | 30 months |
Lemon MA et al. [18] | 12 | UCD (HV) | Chest (Mediastinum) | Yes, complete | Prednisone Cyclophosphamide Plasmapheresis | Survive | Not available |
Wang J et al. [19] | 13 14 | 17/M UCD (HV) 17/F UCD (HV) | Retroperitoneal Chest (Mediastinum) | Yes, complete Yes, complete | Not available Immunoglobulin | Not available Not available | Not available Not available |
Kumar S et al. [20] | 15 | UCD | Extra peritoneal region of right hemipelvis | Yes, complete | Steroids | Survive | Not available |
Coulson IH et al. [21] | 16 | UCD (MX) | Retroperitoneal | Yes, complete | Prednisone | Survive | Not available |
Velasco et al. [22] | 17 | UCD (HV) | Chest (Mediastinum) | Yes, complete | Corticosteroids Rituximab Immunoglobulin Lung transplantation | Death | 34 months |
Sathishkumar et al. [23] | 18 19 | 8/F UCD (HV) 8/M UCD (HV) | Retroperitoneal Cervical | Yes, complete Yes, complete | Prednisone Methotrexate Prednisone | Survive Survive | Not available Not available |