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Table 2 Adverse reactions of included studies

From: The efficacy and safety of fluconazole in preventing invasive fungal infection in very low birth weight infants: a systematic review and meta-analysis

Adverse reactions

Control group

(cases/toal paitents)

Experimental group

(cases/toal paitents)

Heterogeneity test

RR(95%CI)

p

I 2

P

Abnormal liver function

66/608

64/739

0

0.82

0.90(0.67 ~ 1.20)

0.46

Sepsis

207/420

242/547

6%

0.36

0.94(0.82 ~ 1.07)

0.36

Necrotizing enterocolitis

43/420

46/547

0

0.60

0.90(0.60 ~ 1.34)

0.60

Bronchopulmonary dysplasia

135/370

164/497

55%

0.11

0.99(0.84 ~ 1.17)

0.93

Patent ductus arteriosus

61/329

83/454

4%

0.35

1.03(0.75 ~ 1.42)

0.86

Retinopathy of prematurity

72/420

84/547

28%

0.24

0.91(0.64 ~ 1.29)

0.60