Table 2 Frequency of C3435T and G2677T genotypes and allelic polymorphisms in KTRs (AR, non-AR groups) and controls
|  | All KTRs (n = 83) | AR group (n = 36) | None AR group (n = 47) | Controls (n = 80) | AR vs. None AR | AR vs. Controls | None AR vs. Controls | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
N (%) | N (%) | N (%) | N (%) | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |||
C3435T | Genotype | TT | 22 (26.5) | 3 (8.3) | 19 (40.4) | 24 (30) | Reference | - | Reference | - | Reference | - |
CT | 35 (42.2) | 20 (55.6) | 15 (31.9) | 40 (50) | 3.58 (1.64–7.80) | 0.001 | 2.20 (1.08–4.46) | 0.028 | 0.63 (0.37–1.06) | 0.082 | ||
CC | 26 (31.3) | 13 (36.1) | 13 (27.7) | 16 (20) | 2.99 (1.32–6.75) | 0.008 | 2.98 (91.37–6.46) | 0.006 | 1.02 (0.56–1.83) | 0.957 | ||
Allele | T | 79 (47.6) | 26 (36.1) | 53 (56.4) | 88 (55) | Reference | - | Reference | - | Reference | - | |
C | 87 (52.4) | 46 (63.9) | 41 (43.6) | 72(45) | 1.67 (1.13–2.46) | 0.010 | 1.59 (1.13–2.24) | 0.008 | 0.97 (0.70–1.32) | 0.83 | ||
G2677T | Genotype | GG | 23 (27.7 | 5 (13.9) | 18 (38.3) | 39 (48.8) | Reference | - | Reference | - | Reference | - |
GT | 37 (44.6 | 19 (52.8) | 18 (38.3) | 28 (35) | 2.259 (1.12–4.555) | 0.023 | 2.625 (1.43–4.817) | 0.002 | 1.226 (0.743–2.021) | 0.425 | ||
TT | 23 (27.7) | 12 (33.3) | 11 (23.4) | 13 (16.3) | 2.306 (1.069–4.975) | 0.033 | 3.181 (1.592–6.356) | 0.001 | 1.455 (0.793–2.668) | 0.226 | ||
Allele | G | 83 (50) | 29 (40.3) | 54 (57.4) | 106 (66.3) | Reference | - | Reference | - | Reference | - | |
T | 83 (50) | 43 (59.7) | 40 (42.6) | 54 (33.8) | 1.541 (1.047–2.268) | 0.028 | 1.91 (1.353–2.697) | < 0.001 | 1.261 (0.911–1.744) | 0.162 | ||