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Table 2 Demographic and clinical features of patients affected by primary adrenal insufficiency (PAI) and central adrenal insufficiency (CAI).

From: Adrenal insufficiency management in the pediatric emergency setting and risk factors for adrenal crisis development

 

PAI

CAI

p value

Gender (M/F)

28/16

28/17

0.89

Age at diagnosis (years)

1.72 ± 0.58

5.32 ± 0.77

0.0003

Age at ED access (years)

5.56 ± 1.03

5.37 ± 1.04

0.89

Steroid dose (mg/mq/day)

13.7 ± 0.95

14.3 ± 0.73

0.65

At home steroid management

   

No change

26

19

0.94

Double oral dose

6

5

Triple oral dose

8

6

Intramuscular

2

0

No therapy

2

3

Symptoms duration - from onset to ED admission (hours)

5 ± 1.4

28 ± 3.8

0.005

 N. of admissions

44

33

 

Single admission

7

4

0.51

2 admissions

8

4

3 admissions

3

3

4 admissions

3

3

Glucose value (mg/dl)

73.6 ± 10.9

84.8 ± 12.4

0.5

Sodium value (mmol/l)

137.2 ± 1.23

133.3 ± 1.46

0.05

Patients with adrenal crisis

10

3

0.06

Adrenal crisis episodes

12

14

0.57