Table 2 Summary of studies including instrumental objective parameters concerning asthma
From: Pediatric asthma and altitude: a complex interplay between different environmental factors
Reference (year of publication) | Study population (n) | Environments examined | Main study outcomes |
|---|---|---|---|
Sporik et al. (1995) [36] | 525 in Phase 1, 120 in Phase 2 | USA, a city at 2,195 m of altitude | Questionnaire assessing asthma prevalence, asthma therapy, ER visits and hospital admission due to asthma, SPT for aeroallergens, serum total IgE dosage, baseline spirometry, bronchial hyperresponsiveness testing and bronchodilator test |
Giroux et al. (2001) [37] | 126 | France, a city at 141 m and a specialized residential centre in a mountain area at 1000 m | FeNO |
Giroux et al. (2002) [40] | 140 | France, a city at 141 m and a specialized residential centre in a mountain area at 1000 m | FeNO, expired NH3, urinary NH4+, sodium, potassium and urea |
Ramirez et al. (2021) [41] | 93 | Bogota, Colombia (2640 m) | Several IOS and spirometric parameters at baseline and after bronchodilator |