Fig. 6
From: Novel mutations in CYBB Gene Cause X-linked chronic Granulomatous Disease in Pakistani patients
Defective control of the proliferation of M. tuberculosis by MDMs from gp91phox functional deficient patients is improved by rhIFN-γ. The results of untreated (-) and rhIFN-γ treated (rhIFN-γ) MDMs are shown (A) Phagocytosis, (B) M. tuberculosis growth index. The bacterial proliferation index was determined based on the ratio of the CFU numbers on day 6 to the CFU number on day 0 after the challenge (Control N = 5 and Patients N = 5). - indicating without rhIFN-γ treatment of MDMs