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Table 2 Predictive values in ROC analysis

From: Clinical value of combined serum CA125, NSE and 24-hour urine VMA for the prediction of recurrence in children with neuroblastoma

 

Cut-off value

AUC (95% CI)

p

Sensitivity (%)

Specificity (%)

Youden index

Serum CA125

79.93

0.71 (0.64 to 0.77)

< 0.001

52.94

87.12

0.40

Serum NSE

63.69

0.74 (0.68 to 0.80)

< 0.001

59.80

79.75

0.39

24-hour urine VMA

79.95

0.76 (0.70 to 0.82)

< 0.001

71.57

71.17

0.43

Model*

-

0.91 (0.87 to 0.95)

< 0.001

83.33

88.34

0.72

  1. CI: confidence interval
  2. *Logit (Model) = 0.032 * NSE + 0.027 * CA125 + 0.030 * VMA