Table 1 Demographics and clinical characteristics of RSV-hospitalized patients 2011–2020. Policlinico Foggia, Apulia region, Italy
Characteristics | Number* (N = 832) | (%) | 95% CI |
|---|---|---|---|
Sex | Â | Â | Â |
Male | 470 | 56.5 | 53.0–59.9 |
Female | 362 | 43.5 | 40.1–46.9 |
Age, months | Â | Â | Â |
Median age (IQR) | 3 (1–11) |  |  |
Age group (months) | Â | Â | Â |
0–2 | 413 | 49.6 | 46.4–53.3 |
3–5 | 121 | 14.5 | 12.2–17.1 |
6–11 | 96 | 11.5 | 9.6–14.0 |
12–23 | 96 | 11.5 | 9.0–13.4 |
24–59 | 97 | 11.7 | 9.0–14.2 |
> 59 | 9 | 1.1 | 0.5–2.0 |
Hospitalization year | Â | Â | Â |
2011 | 60 | 7.2 | 5.6–9.2 |
2012 | 46 | 5.5 | 4.2–7.3 |
2013 | 69 | 8.3 | 6.5–10.3 |
2014 | 89 | 10.7 | 8.7–12.9 |
2015 | 113 | 13.6 | 11.4–16.0 |
2016 | 90 | 10.8 | 8.9–13.1 |
2017 | 113 | 13.6 | 11.4–16.1 |
2018 | 98 | 11.8 | 9.7–14.1 |
2019 | 111 | 13.3 | 11.1–15.8 |
2020 | 43 | 5.2 | 3.8–6.9 |
Type specimens | Â | Â | Â |
Nasopharyngeal swab | 811 | 97.5 | 96.0–98.3 |
Bronchoalveolar lavage fluid | 10 | 1.2 | 0.6–2.2 |
Tracheal wash | 11 | 1.3 | 0.7–2.3 |
RSV subtypes | Â | Â | Â |
A | 474 | 57.0 | 53.6–60.3 |
B | 358 | 43.0 | 39.6–46.4 |
Admission unit | Â | Â | Â |
Pediatric | 653 | 78.5 | 74.3–81.2 |
Neonatal intensive care | 179 | 21.5 | 18.8–24.6 |
Clinical categorization | Â | Â | Â |
Bronchiolitis | 527 | 63.3 | 59.9–66.6 |
Pneumonia | 152 | 18.3 | 15.7–21.1 |
Acute upper respiratory infections due to RSV | 67 | 8.1 | 6.3–10.1 |
Unspecified respiratory disease due to RSV | 37 | 4.4 | 3.11–6.1 |
Unspecified respiratory disease | 49 | 5.9 | 4.39–7.71 |
LOS | Â | Â | Â |
Median (IQR) | 5 (3–7) |  |  |
Frequency per days | Â | Â | Â |
0–1 days | 20 | 2.4 | 1.5–3.7 |
2 days | 86 | 10.3 | 8.3–12.6 |
3–4 days | 260 | 31.2 | 28.1–34.5 |
≥ 5 days | 466 | 56.0 | 40.7–47.6 |
Very severe RSV disease* | 208 | 25.0 | 22.1–28.1 |
2011 | 14 | 6.7 | 3.7–11.0 |
2012 | 13 | 6.3 | 3.4–10.4 |
2013 | 17 | 8.2 | 4.8–12.7 |
2014 | 18 | 8.7 | 5.2–13.3 |
2015 | 16 | 7.7 | 4.5–12.2 |
2016 | 15 | 7.2 | 4.1–11.6 |
2017 | 35 | 16.8 | 12.0-22.6 |
2018 | 32 | 15.4 | 10.8–21.0 |
2019 | 35 | 16.8 | 12.0-22.6 |
2020 | 13 | 6.3 | 3.4–10.4 |
Severity measures | Â | Â | Â |
NICU admission | 179 | 21.5 | 18.8–24.6 |
Mechanical ventilation | 35 | 4.2 | 2.9–5.8 |
Respiratory therapy | 99 | 11.9 | 9.8–14.3 |
ECMO | 0 | 0 | - |
Deaths | 1 | 0.1 | 0.003–0.7 |
Delivery during the RSV infection season | 532 | 63.9 | 60.6–67.2 |
Comorbid condition | Â | Â | Â |
Pediatric CCCs | 125 | 15.0 | 12.7–17.6 |
History of prematurity | 70 | 8.4 | 6.6–10.5 |