Fig. 1

Clinical features of cutaneous manifestations of epidermolysis bullosa (EB). Serous blisters on erythematous skin in an arcuate distribution on the neck of a 4-year-old male affected with severe EB simplex (a); extensive erosions and peripheral blisters on the lower back, buttocks and lower limbs of a two-day-old newborn with severe junctional EB, these lesions are painful and at high risk of infection (b); extensive chronic and painful wound with exuberant granulation tissue, partially surrounded by crusts, on the nape and upper back of a 9-year-old girl affected with severe recessive dystrophic EB (c); disabling mitten hand deformity, typical of recessive dystrophic EB in an adult women (d)