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  1. Along with the wide spread application and technical development of the flexible and rigid bronchoscopy, the airway foreign body removing method cme to the specific technique for different foreign bodies from ...

    Authors: Lin-Lin Han, Chen Meng, Zhong-Xiao Zhang, Xiao-Di Tang, Jing Ma and Chang-Xiao Li
    Citation: Italian Journal of Pediatrics 2022 48:159
  2. Mutations in the neuronal sodium voltage-gated channel, alpha subunit 1 (SCN1A) gene have been associated with epilepsy. We investigated the SCN1A-A3184G polymorphism among Egyptian children and adolescents with ...

    Authors: Esraa Ghazala, Doaa A. Shahin and Yahya Wahba
    Citation: Italian Journal of Pediatrics 2022 48:157
  3. Cyclic Vomiting Syndrome (CVS) is a rare functional gastrointestinal disorder, which has a considerable burden on quality of life of both children and their family. Aim of the study was to evaluate the diagnos...

    Authors: Sara Isoldi, Giovanni Di Nardo, Saverio Mallardo, Pasquale Parisi, Umberto Raucci, Renato Tambucci, Paolo Quitadamo, Silvia Salvatore, Enrico Felici, Fabio Cisarò, Licia Pensabene, Claudia Banzato, Caterina Strisciuglio, Claudio Romano, Patrizia Fusco, Francesca Rigotti…
    Citation: Italian Journal of Pediatrics 2022 48:156
  4. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has been challenging health care systems and made it necessary to use rapid and cost-effective testing methods, particularly in Emergency D...

    Authors: Angela Pepe, Francesco Valitutti, Deborah Veneruso, Martina Bove, Anna Giulia Elena De Anseris, Lucia Nazzaro, Pasquale Pisano, Daniela Melis and Claudia Mandato
    Citation: Italian Journal of Pediatrics 2022 48:155
  5. CHARGE syndrome (CS) is an autosomal dominant genetic condition whose recognition in the neonatal period is complicated by considerable phenotypic variability. Pediatric patients with genetic disorders have a ...

    Authors: Alessandra Consales, Beatrice Letizia Crippa, Lorenzo Colombo, Roberta Villa, Francesca Menni, Claudia Giavoli, Fabio Mosca and Maria Francesca Bedeschi
    Citation: Italian Journal of Pediatrics 2022 48:154
  6. Mycoplasma pneumoniae pneumonia (MPP) is a prevalent disease in community-acquired pneumonia among children. However, in addition to respiratory manifestations, it may also develop extra-pulmonary complications. ...

    Authors: Chunjiao Han, Tongqiang Zhang, Jiafeng Zheng, Peng Jin, Qi Zhang, Wei Guo and Yongsheng Xu
    Citation: Italian Journal of Pediatrics 2022 48:153
  7. Noonan and Noonan-like syndromes are multisystem genetic disorders, mainly with autosomal dominant trasmission, caused by mutations in several genes. Missense pathogenetic variants of SOS1 gene are the second ...

    Authors: Francesca Mercadante, Ettore Piro, Martina Busè, Emanuela Salzano, Arturo Ferrara, Gregorio Serra, Cristina Passarello, Giovanni Corsello and Maria Piccione
    Citation: Italian Journal of Pediatrics 2022 48:152
  8. The impact of socio-economic status on the risk of allergy in African children is not clear.

    Authors: Chiara Zuiani, Michele Arigliani, Ramatu Zubair, Livingstone Gayus Dogara, Luigi Castriotta, Ashel Dache Sunday, Reward Christopher Audu, Habibah Dadan-Garba, Zakary Sani, Baba Inusa and Paola Cogo
    Citation: Italian Journal of Pediatrics 2022 48:151
  9. During the first and second COVID-19 pandemic waves, children, despite susceptible to SARS-CoV-2 infection, appeared at lower risk of severe disease, hospitalization, and death than adults and the elderly. Mor...

    Authors: Susanna Esposito, Rosanna Giordano, Giulia Paini, Matteo Puntoni, Nicola Principi and Caterina Caminiti
    Citation: Italian Journal of Pediatrics 2022 48:150
  10. Chronic kidney disease stage 5 (CKD 5) populations have peculiar risk for severe Covid-19 infection. Moreover; pediatric data are sparse and lacking. The aim of this study is to report our experience in CKD 5 ...

    Authors: Fatina I. Fadel, Samar Sabry, Mohamed A. Abdel Mawla, Rasha Essam Eldin Galal, Doaa M. Salah, Rasha Helmy, Yasmen Ramadan, Wessam Elzayat, May Abdelfattah and Eman Abobakr Abd Alazem
    Citation: Italian Journal of Pediatrics 2022 48:149
  11. Adenosine deaminase (ADA) is an enzyme involved in purine metabolism with an important role in cellular immunity. Thus, this study investigated the association between ADA and Epstein–Barr virus (EBV)-related ...

    Authors: Ting Shi, Yu Shen, Wei Zhang, Meiying Qian, Xiuli Chen, Linlin Huang and Jianmei Tian
    Citation: Italian Journal of Pediatrics 2022 48:148
  12. The aim of our study was to better define the clinical pattern of diencephalic syndrome, a rare but potentially lethal cause of failure to thrive in infancy. Poor weight gain or weight loss, the characteristic...

    Authors: Sandra Trapani, Barbara Bortone, Martina Bianconi, Chiara Rubino, Iacopo Sardi, Paolo Lionetti and Giuseppe Indolfi
    Citation: Italian Journal of Pediatrics 2022 48:147
  13. The practice of therapeutic hypothermia (TH) is widely used for neonatal hypoxic-ischemic encephalopathy (HIE) despite its corresponding feeding strategies are still controversial. This randomized controlled t...

    Authors: Ya Hu, Feng Chen, Xinyu Xiang, Fang Wang, Ziyu Hua and Hong Wei
    Citation: Italian Journal of Pediatrics 2022 48:146
  14. Congenital ichthyosis (CI) is a heterogeneous group of genetic disorders characterized by generalized dry skin, scaling and hyperkeratosis, often associated to erythroderma. They are rare diseases, with overal...

    Authors: Gregorio Serra, Luigi Memo, Paola Cavicchioli, Mario Cutrone, Mario Giuffrè, Maria Laura La Torre, Ingrid Anne Mandy Schierz and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:145
  15. During the Coronavirus-19 disease (Covid-19) pandemic it was observed that the number of girls presenting with early puberty had increased. The aim of this study was to carry out a retrospective evaluation of ...

    Authors: Gul Yesiltepe Mutlu, Elif Eviz, Belma Haliloglu, Heves Kirmizibekmez, Fatma Dursun, Servan Ozalkak, Atilla Cayir, Beste Yuksel Sacli, Mehmet Nuri Ozbek, Huseyin Demirbilek and Sukru Hatun
    Citation: Italian Journal of Pediatrics 2022 48:144
  16. Nutrition in the first 1000 days of life is essential to ensure appropriate growth rates, prevent adverse short- and long-term outcomes, and allow physiologic neurocognitive development. Appropriate management...

    Authors: Maria Elisabetta Baldassarre, Raffaella Panza, Francesco Cresi, Guglielmo Salvatori, Luigi Corvaglia, Arianna Aceti, Maria Lorella Giannì, Nadia Liotto, Laura Ilardi, Nicola Laforgia, Luca Maggio, Paolo Lionetti, Carlo Agostoni, Luigi Orfeo, Antonio Di Mauro, Annamaria Staiano…
    Citation: Italian Journal of Pediatrics 2022 48:143
  17. From March 2020 to July 2022, in Liguria region (North-West Italy) incidence of MIS-C among pediatric patients infected by SARS-CoV-2 was 38.7/100.000, which is higher than that of myocarditis after COVID-19 v...

    Authors: Marcello Mariani, Roberta Caorsi, Alessandro Consolaro, Giacomo Brisca, Camilla Sticchi, Marco Gattorno, Elio Castagnola and Angelo Ravelli
    Citation: Italian Journal of Pediatrics 2022 48:142
  18. Cystic fibrosis (CF) is the most common inherited disease in Caucasian populations, affecting around 50,000 patients in Europe and 30,000 in United States. A mutation in CF trans-membrane conductance regulator (C...

    Authors: Vito Terlizzi, Chiara Castellani, Giovanni Taccetti and Beatrice Ferrari
    Citation: Italian Journal of Pediatrics 2022 48:141
  19. Infantile hemangiomas may affect the quality of life (QoL) of patients and their family members, as anxiety and worry may commonly occur in parents, also linked to the social adversion they experience. We unde...

    Authors: Marco Pensabene, Maria Rita Di Pace, Fabio Baldanza, Francesco Grasso, Maria Patti, Maria Sergio, Simona La Placa, Mario Giuffre’, Gregorio Serra, Alessandra Casuccio and Marcello Cimador
    Citation: Italian Journal of Pediatrics 2022 48:140
  20. Primary Synovial Chondromatosis (PSC) is a rare benign tumor of the synovial membrane in which cartilage metaplasia produces calcific loose bodies within the articular space. Only a few cases are reported in t...

    Authors: Matteo Trevisan, Luca Di Lenarda, Serena Pastore, Alessia Saccari, Gianluca Canton, Umberto Lucangelo, Andrea Taddio and Luigi Murena
    Citation: Italian Journal of Pediatrics 2022 48:139
  21. Recent research has documented the potential associations existing between the use of social media (SM) and the occurrence/development and treatment of Eating Disorders (ED). However, the literature directly a...

    Authors: Jacopo Pruccoli, Marta De Rosa, Lucia Chiasso, Annalisa Perrone and Antonia Parmeggiani
    Citation: Italian Journal of Pediatrics 2022 48:138
  22. Considering the destructive effects of malnutrition on the growth, development, and health of children and the importance of identifying the factors affecting it, the present study aimed to investigate the sta...

    Authors: Mina Maheri, Maryam Bidar, Hamidreza Farrokh-Eslamlou and Ali Sadaghianifar
    Citation: Italian Journal of Pediatrics 2022 48:137
  23. The COVID-19 pandemic has dramatically affected healthcare professionals’ lives. We investigated the potential mental health risk faced by healthcare professionals working in neonatal units in a multicentre cr...

    Authors: Luigi Gagliardi, Serena Grumi, Marzia Gentile, Roberta Cacciavellani, Giulia Placidi, Angelina Vaccaro, Claudia Maggi, Beatrice Gambi, Letizia Magi, Laura Crespin, Graziano Memmini, Marcello DeFilippo, Elena Verucci, Liliana Malandra, Laura Mele, Angelo Azzarà…
    Citation: Italian Journal of Pediatrics 2022 48:136
  24. Childhood obesity is associated with impaired Quality-of-Life (QoL), increased stigmatization and higher risk of development of depression compared to their peers. This report describes the long-term developme...

    Authors: Rasmus Møller Jørgensen, Esben Thyssen Vestergaard, Britta Kremke, Rikke Frederiksen Bahnsen, Bent Windelborg Nielsen and Jens Meldgaard Bruun
    Citation: Italian Journal of Pediatrics 2022 48:135
  25. Authors: Adriano La Vecchia, Giulio Ippolito, Vittoria Taccani, Elisabetta Gatti, Patrizia Bono, Silvia Bettocchi, Raffaella Pinzani, Claudia Tagliabue, Samantha Bosis, Paola Marchisio and Carlo Agostoni
    Citation: Italian Journal of Pediatrics 2022 48:134

    The original article was published in Italian Journal of Pediatrics 2022 48:67

  26. Arthrogryposis multiplex congenita (AMC) is a group of clinically and etiologically heterogeneous conditions, characterized by prenatal onset contractures affecting two or more joints. Its incidence is about 1...

    Authors: Gregorio Serra, Vincenzo Antona, Chiara Cannata, Mario Giuffrè, Ettore Piro, Ingrid Anne Mandy Schierz and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:133
  27. Congenital maxillomandibular syngnathia is a rare craniofacial anomaly leading to difficulties in feeding, breathing and ability to thrive. The fusion may consist of soft tissue union (synechiae) to hard tissu...

    Authors: Ingrid Anne Mandy Schierz, Salvatore Amoroso, Vincenzo Antona, Mario Giuffrè, Ettore Piro, Gregorio Serra and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:132
  28. Congenital hypothyroidism (CH) is the most frequent congenital endocrine disorder. The purpose of the present study was to evaluate the incidence and etiological classification of CH in Apulia in a three-year ...

    Authors: Simonetta Simonetti, Gabriele D’Amato, Benedetta Esposito, Mariangela Chiarito, Domenico Dentico, Tania Lorè, Roberta Cardinali, Silvia Russo, Nicola Laforgia and Maria Felicia Faienza
    Citation: Italian Journal of Pediatrics 2022 48:131
  29. The ongoing Coronavirus Disease 2019 (COVID-19) epidemic represents an unprecedented global health challenge. Many COVID-19 symptoms are similar to symptoms that can occur in other infections. Malaria should a...

    Authors: Michela Scalisi, Salvatore Giordano, Laura Antonella Canduscio, Maria Concetta Failla, Luca Messina, Elisa Sferrazza, Raffaella Rubino, Lucia Siracusa, Veronica Vanella, Antonio Cascio and Claudia Colomba
    Citation: Italian Journal of Pediatrics 2022 48:130
  30. We proposed to analyze thoroughly the impact of the COVID-19 lockdown (CL) in changes of profiles and in trend of the domestic accidents (DAs) in children.

    Authors: Valentina Ferro, Raffaella Nacca, Mara Pisani, Sebastian Cristaldi, Maria Francesca Faa, Maria Chiara Supino, Umberto Raucci, Antonino Reale, Marta Ciofi Degli Atti, Massimiliano Raponi, Alberto Villani and Anna Maria Musolino
    Citation: Italian Journal of Pediatrics 2022 48:129
  31. Leukoencephalopathy with vanishing white matter (VWM) is an autosomal recessive neurological disease. The physiopathology of disease is still little understood, but it seems to involve impairment in maturation...

    Authors: Ilaria Filareto, Giulia Cinelli, Ilaria Scalabrini, Elisa Caramaschi, Patrizia Bergonzini, Elisabetta Spezia, Alessandra Todeschini and Lorenzo Iughetti
    Citation: Italian Journal of Pediatrics 2022 48:128
  32. According to the latest version of the Diagnostic and Statistical Manual of Mental Disorders, somatic symptom and related disorders (SSRDs) are defined as psychopathological manifestations characterized by phy...

    Authors: Roberta Sartori, Antimo Tessitore, Aurora Della Torca and Egidio Barbi
    Citation: Italian Journal of Pediatrics 2022 48:127
  33. Quarantine and isolation measures during COVID-19 pandemic may have caused additional stress and challenged the mental health of the youth. Aim of the study is to investigate the COVID-19 pandemic impact on ne...

    Authors: Elena Bozzola, Pietro Ferrara, Giulia Spina, Alberto Villani, Marco Roversi, Massimiliano Raponi, Giovanni Corsello and Annamaria Staiano
    Citation: Italian Journal of Pediatrics 2022 48:126
  34. Neurological vertigo is a common symptom in children and adults presenting to the emergency department (ED) and its evaluation may be challenging, requiring often the intervention of different medical specialt...

    Authors: Noemi Pellegrino, Vincenzo Di Stefano, Eleonora Rotondo, Alessandro Graziosi, Marianna Gabriella Rispoli, Angelo Torrente, Antonino Lupica, Filippo Brighina, Umberto Raucci and Pasquale Parisi
    Citation: Italian Journal of Pediatrics 2022 48:125
  35. Ventricular septal defects (VSDs) are one of the leading causes of death due to cardiac anomalies during the first months of life. The prevalence of VSD in neonates is reported up to 4%. Despite the remarkable...

    Authors: Sumbal Sarwar, Shabana, Amna Tahir, Zainab Liaqat, Saher Naseer, Rani Summeya Seme, Sabahat Mehmood, Saleem Ullah Shahid and Shahida Hasnain
    Citation: Italian Journal of Pediatrics 2022 48:124
  36. Albright’s hereditary osteodystrophy (AHO) is an inherited disorder which is caused by an inactivating variant in the GNAS gene. AHO appears associated to either pseudohypoparathyroidism 1a (PHP1a) when GNAS gene...

    Authors: Qing Zhou, Bin Liang, Qing-Xian Fu, Hui Liu and Chao-Chun Zou
    Citation: Italian Journal of Pediatrics 2022 48:123
  37. With the increasing incidence of asymptomatic carriers or milder symptoms, children and adolescents are likely to become a silent source of infection. In view of the efficacy and safety of vaccines in the trea...

    Authors: Lin Wang, Wen Wen, Chen Chen, Jiake Tang, Chunyi Wang, Mengyun Zhou, Yongran Cheng, Xingwei Zhang, Mingwei Wang, Zhanhui Feng and Weiqian Wang
    Citation: Italian Journal of Pediatrics 2022 48:122
  38. Prader-Willi syndrome (PWS) is a complex disorder caused by impaired paternally expressed genes on chromosome 15q11-q13. Variable findings have been reported about the phenotypic differences among PWS genetic ...

    Authors: Lu Zhang, Xiaoliang Liu, Yunjing Zhao, Qingyi Wang, Yuanyuan Zhang, Haiming Gao, Bijun Zhang, Wanting Cui and Yanyan Zhao
    Citation: Italian Journal of Pediatrics 2022 48:121
  39. The bacterial load of the human lower respiratory tract is at least several times lower than that of the other parts of the body. This study aimed to identify the bacterial composition and colony structure of ...

    Authors: Jiawei Yao, Tao Ai, Wanmin Xia, Yinghong Fan, Cheng Xie and Lei Zhang
    Citation: Italian Journal of Pediatrics 2022 48:120
  40. E-cigarettes are devices which allow to aerosolize liquids containing nicotine or other substances. Ever since they were released on the market in 2006, the number of users have been constantly increasing, esp...

    Authors: Chiara Casamento Tumeo, Alessandra Schiavino, Maria Giovanna Paglietti, Francesca Petreschi, Alessandra Ottavianelli, Alessandro Onofri, Claudio Cherchi, Paolo Tomà and Renato Cutrera
    Citation: Italian Journal of Pediatrics 2022 48:119
  41. The rate of chronic drooling in children older than 4 years is 0.5%, but it rises to 60% in those with neurological disorders. Physical and psychosocial consequences lead to a reduction in the quality of Life ...

    Authors: Antonella Riva, Elisabetta Amadori, Maria Stella Vari, Alberto Spalice, Vincenzo Belcastro, Maurizio Viri, Donatella Capodiferro, Antonino Romeo, Alberto Verrotti and Pasquale Striano
    Citation: Italian Journal of Pediatrics 2022 48:118
  42. Preterm extremely low birth weight infants (ELBWi) are known to be at greater risk of developing neuropsychiatric diseases. Identifying early predictors of outcome is essential to refer patients for early inte...

    Authors: Camilla Caporali, Stefania Longo, Giovanna Tritto, Gianfranco Perotti, Camilla Pisoni, Cecilia Naboni, Barbara Gardella, Arsenio Spinillo, Federica Manzoni, Stefano Ghirardello, Renato Borgatti and Simona Orcesi
    Citation: Italian Journal of Pediatrics 2022 48:117
  43. Hypokalemic periodic paralysis is a rare neuromuscular genetic disorder due to defect of ion channels and subsequent function impairment. It belongs to a periodic paralyses group including hyperkalemic periodi...

    Authors: Maria Carolina Colucci, Marica Fabiana Triolo, Simona Petrucci, Flaminia Pugnaloni, Massimiliano Corsino, Melania Evangelisti, Maria Cecilia D’Asdia, Giovanni Di Nardo, Matteo Garibaldi, Gianluca Terrin and Pasquale Parisi
    Citation: Italian Journal of Pediatrics 2022 48:116
  44. It is now well established that atherosclerosis begins in childhood and evolves through adolescence and young adulthood, ultimately resulting in myocardial infarction and stroke in adults.

    Authors: Giuseppe Banderali, Maria Elena Capra, Giacomo Biasucci, Rita Stracquadaino, Claudia Viggiano and Cristina Pederiva
    Citation: Italian Journal of Pediatrics 2022 48:115
  45. Despite simple and proven cost-effective measures were available to prevent birth asphyxia; studies suggested that there has been limited progress in preventing birth asphyxia even in healthy full-term neonate...

    Authors: Masresha Asmare Techane, Tewodros Getaneh Alemu, Chalachew Adugna Wubneh, Getaneh Mulualem Belay, Tadesse Tarik Tamir, Addis Bilal Muhye, Destaye Guadie Kassie, Amare Wondim, Bewuketu Terefe, Bethelihem Tigabu Tarekegn, Mohammed Seid Ali, Beletech Fentie, Almaz Tefera Gonete, Berhan Tekeba, Selam Fisiha Kassa, Bogale Kassahun Desta…
    Citation: Italian Journal of Pediatrics 2022 48:114
  46. Studies published on gender-related differences in the gambling behavior of adolescents have focused mainly on psychological and social factors. The aim of this study was to develop separate risk factor models...

    Authors: Alessandra Buja, Milena Sperotto, Bruno Genetti, Paolo Vian, Fabio Vittadello, Elisabetta Simeoni, Chiara Zampieri and Vincenzo Baldo
    Citation: Italian Journal of Pediatrics 2022 48:113
  47. Autism spectrum disorder (ASD) is one of the serious developmental disorders that is usually diagnosed below the age of three years. Although the severity of the disease’s symptoms varies from patient to patie...

    Authors: Nader Salari, Shabnam Rasoulpoor, Shna Rasoulpoor, Shamarina Shohaimi, Sima Jafarpour, Nasrin Abdoli, Behnam Khaledi-Paveh and Masoud Mohammadi
    Citation: Italian Journal of Pediatrics 2022 48:112
  48. Cathelicidin/LL-37 plays a significant role in the human immune defense reaction. Preterm human immature organs being exposed to inflammation-induced injury was the critical denominator leading to the common p...

    Authors: Zhuxiao Ren, Wenhui Mo, Liling Yang, Jianlan Wang, Qi Zhang, Zhicheng Zhong, Wei Wei, Zhipeng Liu, Zhiping Wu, Yao Yao and Jie Yang
    Citation: Italian Journal of Pediatrics 2022 48:111
  49. Available guidelines for asthma management represent an important and suitable tool to make the entire medical process evidence-based, effective, and safe for patients. Their purpose is to help doctors and pat...

    Authors: Elio Novembre, Mattia Giovannini, Simona Barni and Francesca Mori
    Citation: Italian Journal of Pediatrics 2022 48:110
  50. Adolescence is characterized by emotional instability and risk-taking behaviours that can lead to, among other things, an increased risk of developing pathological video-gaming and gambling habits. The aim of ...

    Authors: Loredana Cena, Matteo Rota, Stefano Calza, Alice Trainini, Sara Zecca, Sofia Bonetti Zappa, Luisa Silvia Nodari and Alberto Stefana
    Citation: Italian Journal of Pediatrics 2022 48:108

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