This section considers studies regarding all aspects of endocrinology and diabetology in children and adolescents.

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  1. Review

    The link between obesity and migraine in childhood: a systematic review

    Obesity and headache are two highly prevalent diseases both in adults and children and they are associated with a strong personal and social impact. Many studies suggest that obesity is comorbid with headache ...

    G. Farello, P. Ferrara, A. Antenucci, C. Basti and A. Verrotti

    Italian Journal of Pediatrics 2017 43:27

    Published on: 7 March 2017

  2. Research

    Percentiles of serum uric acid and cardiometabolic abnormalities in obese Italian children and adolescents

    To investigate the association of serum uric acid (SUA) with cardiometabolic abnormalities in Caucasian overweight/obese children (<10 years of age) versus adolescents (≥10 years of age) by drawing age and gen...

    Rosa Luciano, Blegina Shashaj, MariaRita Spreghini, Andrea Del Fattore, Carmela Rustico, Rita Wietrzykowska Sforza, Giuseppe Stefano Morino, Bruno Dallapiccola and Melania Manco

    Italian Journal of Pediatrics 2017 43:3

    Published on: 3 January 2017

  3. Commentary

    Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children

    Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is...

    Mariella Valenzise, Tommaso Aversa, Giuseppina Zirilli, Giuseppina Salzano, Domenico Corica, Simona Santucci and Filippo De Luca

    Italian Journal of Pediatrics 2017 43:2

    Published on: 3 January 2017

  4. Research

    No effect of yeast-like fungi on lipid metabolism and vascular endothelial growth factor level in children and adolescents with type 1 diabetes mellitus

    The objective of the research was to investigate vascular endothelial growth factor (VEGF) levels in the context of lipid metabolism and amount of yeast-like fungi colonizing the digestive tract in children an...

    Katarzyna Zorena, Beata Kowalewska, Małgorzata Szmigiero-Kawko, Piotr Wąż and Małgorzata Myśliwiec

    Italian Journal of Pediatrics 2016 42:107

    Published on: 12 December 2016

  5. Research

    Genetic and epigenetic alterations in the GNAS locus and clinical consequences in Pseudohypoparathyroidism: Italian common healthcare pathways adoption

    Genetic and epigenetic alterations in the GNAS locus are responsible for the Gsα protein dysfunctions causing Pseudohypoparathyroidism (PHP) type Ia/c and Ib, respectively. For these heterogeneous diseases charac...

    L. de Sanctis, F. Giachero, G. Mantovani, G. Weber, M. Salerno, G. I. Baroncelli, F. M. Elli, P. Matarazzo, M. Wasniewska, L. Mazzanti, G. Scirè and D. Tessaris

    Italian Journal of Pediatrics 2016 42:101

    Published on: 21 November 2016

  6. Research

    Long-term safety and efficacy of Omnitrope®, a somatropin biosimilar, in children requiring growth hormone treatment: Italian interim analysis of the PATRO Children study

    PATRO Children is an ongoing observational, longitudinal, non-interventional, global post-marketing surveillance study, which is investigating the long-term safety and effectiveness of Omnitrope®, a somatropin...

    Lorenzo Iughetti, Gianluca Tornese, Maria Elisabeth Street, Flavia Napoli, Claudia Giavoli, Franco Antoniazzi, Stefano Stagi, Caterina Luongo, Sara Azzolini, Letizia Ragusa, Gianni Bona, Clara Zecchino, Tommaso Aversa, Luca Persani, Laura Guazzarotti, Emiliano Zecchi…

    Italian Journal of Pediatrics 2016 42:93

    Published on: 3 November 2016

  7. Review

    Peripheral quantitative computed tomography (pQCT) for the assessment of bone strength in most of bone affecting conditions in developmental age: a review

    Peripheral quantitative computed tomography provides an automatical scan analysis of trabecular and cortical bone compartments, calculating not only their bone mineral density (BMD), but also bone geometrical ...

    Stefano Stagi, Loredana Cavalli, Tiziana Cavalli, Maurizio de Martino and Maria Luisa Brandi

    Italian Journal of Pediatrics 2016 42:88

    Published on: 26 September 2016

  8. Research

    The growth and development of children born to adolescent mothers in Taiwan

    Adolescent pregnancy carries a higher risk of adverse birth outcomes. Currently, there are very few longitudinal studies that have investigated the growth of children born to adolescents. This study explores t...

    Wei-Ya Wu, Chi-Rong Li, Ching-Pyng Kuo, Yi-Chen Chiang and Meng-Chih Lee

    Italian Journal of Pediatrics 2016 42:80

    Published on: 31 August 2016

  9. Research

    Congenital primary adrenal insufficiency and selective aldosterone defects presenting as salt-wasting in infancy: a single center 10-year experience

    Salt-wasting represents a relatively common cause of emergency admission in infants and may result in life-threatening complications. Neonatal kidneys show low glomerular filtration rate and immaturity of the ...

    Carla Bizzarri, Nicole Olivini, Stefania Pedicelli, Romana Marini, Germana Giannone, Paola Cambiaso and Marco Cappa

    Italian Journal of Pediatrics 2016 42:73

    Published on: 2 August 2016

  10. Review

    Cell therapies for pancreatic beta-cell replenishment

    The current treatment approach for type 1 diabetes is based on daily insulin injections, combined with blood glucose monitoring. However, administration of exogenous insulin fails to mimic the physiological ac...

    Bernard Okere, Laura Lucaccioni, Massimo Dominici and Lorenzo Iughetti

    Italian Journal of Pediatrics 2016 42:62

    Published on: 11 July 2016

  11. Case report

    Very early onset of autoimmune thyroiditis in a toddler with severe hypothyroidism presentation: a case report

    In infants under 3 years of age acquired primary hypothyroidism caused by autoimmune thyroiditis is very rare. Hypothyroidism can manifest with different signs and symptoms and has a wide range of presentation...

    Pierluigi Marzuillo, Anna Grandone, Silverio Perrotta, Laura Ruggiero, Carlo Capristo, Caterina Luongo, Emanuele Miraglia del Giudice and Laura Perrone

    Italian Journal of Pediatrics 2016 42:61

    Published on: 18 June 2016

  12. Case report

    Failure to thrive as presentation in a patient with 22q11.2 microdeletion

    Abnormalities of chromosome 22q11, including deletions and translocations, have been described in association with different birth defects and malformations occurring in many combinations and degrees of severity.

    Grazia Bossi, Chiara Gertosio, Cristina Meazza, Giovanni Farello and Mauro Bozzola

    Italian Journal of Pediatrics 2016 42:14

    Published on: 11 February 2016

  13. Case report

    Recombinant growth hormone therapy in a girl with costello syndrome: a 4-year observation

    Costello syndrome is a rare syndrome of multiple congenital anomalies. The typical clinical traits include dysmorphic craniofacial features, skin hyperpigmentation and excess, feeding difficulties leading to ...

    Ewa Blachowska, Elżbieta Petriczko, Anita Horodnicka-Józwa, Agata Skórka, Magdalena Pelc, Małgorzata Krajewska-Walasek and Mieczysław Walczak

    Italian Journal of Pediatrics 2016 42:10

    Published on: 26 January 2016

  14. Research

    The effect of two different GH dosages on final height and bone geometry

    Growth hormone (GH) has a strong positive influence on bone, stimulating both bone elongation and increase in size. The aim of the study was to compare the effect of two different GH dosages on final height an...

    Fiorenzo Lupi, Mauro Bozzola, Silvia Longhi, Giovanni Farello and Giorgio Radetti

    Italian Journal of Pediatrics 2016 42:5

    Published on: 15 January 2016

  15. Research

    Metamorphic thyroid autoimmunity in Down Syndrome: from Hashimoto’s thyroiditis to Graves’ disease and beyond

    It is known that Hashimoto’s thyroiditis (HT) may progress to Graves’ disease (GD) and that this phenomenon may be more frequent in the patients with Down syndrome (DS).

    Tommaso Aversa, Mariella Valenzise, Mariacarolina Salerno, Andrea Corrias, Lorenzo Iughetti, Giorgio Radetti, Filippo De Luca and Malgorzata Wasniewska

    Italian Journal of Pediatrics 2015 41:87

    Published on: 11 November 2015

  16. Research

    Final height in Italian patients with congenital hypothyroidism detected by neonatal screening: a 20-year observational study

    Linear growth and final height are reported as normal in congenital hypothyroid patients in the neonatal screening era.

    Maurizio Delvecchio, Maria Cristina Vigone, Malgorzata Wasniewska, Giovanna Weber, Rosa Lapolla, Pietro Pio Popolo, Giulia Maria Tronconi, Raffaella Di Mase, Filippo De Luca, Luciano Cavallo, Mariacarolina Salerno and Maria Felicia Faienza

    Italian Journal of Pediatrics 2015 41:82

    Published on: 28 October 2015

  17. Research

    Five-year response to growth hormone in children with Noonan syndrome and growth hormone deficiency

    Noonan syndrome (NS) is an autosomal dominant disorder characterized by specific features including short stature, distinctive facial dysmorphic features, congenital heart defects, hypertrophic cardiomyopathy,...

    Niki Zavras, Cristina Meazza, Alba Pilotta, Chiara Gertosio, Sara Pagani, Carmine Tinelli and Mauro Bozzola

    Italian Journal of Pediatrics 2015 41:71

    Published on: 6 October 2015

  18. Research

    Chemerin as a novel non-invasive serum marker of intrahepatic lipid content in obese children

    Ectopic hepatic lipid accumulation is closely related to the development of insulin resistance, which is regarded as one of the most significant risk factors of non-alcoholic fatty liver disease (NAFLD). The c...

    Monika Kłusek-Oksiuta, Irena Bialokoz-Kalinowska, Eugeniusz Tarasów, Malgorzata Wojtkowska, Irena Werpachowska and Dariusz Marek Lebensztejn

    Italian Journal of Pediatrics 2014 40:84

    Published on: 17 November 2014

  19. Case report

    Hydrocortisone malabsorption due to polyethylene glycols (Macrogol 3350) in a girl with congenital adrenal insufficiency

    Primary adrenal insufficiency is relatively rare in children and, if unrecognized, may present with cardiovascular collapse, making it a potentially life-threatening entity.

    Stefano Stagi, Paolo Del Greco, Franco Ricci, Chiara Iurato, Giovanni Poggi, Salvatore Seminara and Maurizio de Martino

    Italian Journal of Pediatrics 2014 40:78

    Published on: 26 September 2014

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Società Italiana di Pediatria

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